News

In a new study, researchers in the Netherlands demonstrated that children with cystic fibrosis (CF) have a higher risk of developing human rhinovirus infections, and that these last for longer periods of time than in children without the disease. The research article, titled “Frequency and Duration of Rhinovirus Infections in…

A team of specialists in the United Kingdom are investigating whether a novel hearing test could effectively detect early hearing loss in patients with cystic fibrosis (CF), a possible side effect of antibiotics used to treat recurrent disease-related chest infections. CF is genetic disorder that mostly affects the lungs, and patients are…

A recent Dutch study found preoperative infection or inflammation to be associated with worse outcomes in cystic fibrosis (CF) patients undergoing lung transplantation surgery. This finding might help clinicians better estimate risk before such surgery. The study, titled “Pretransplant HRCT Characteristics Are Associated with Worse Outcome of Lung Transplantation for Cystic Fibrosis Patients,“…

A new study report for a first time an “epidemic spread” of Pandoraea pulmonicola, a bacterial species that belongs to the recently identified genus Pandoraea spp. and which is associated with cystic fibrosis (CF), among patients at a CF center in France. The article, published in BMC Infectious Diseases, is titled “Epidemic spread of Pandoraea pulmonicola in a cystic fibrosis…

A review study suggests that positive expiratory pressure (PEP) devices are more effective than other airway clearance approaches in reducing pulmonary exacerbations in patients with cystic fibrosis (CF), but of similar effectiveness in other measures, like lung function and mucus drainage. The study, entitled “Positive expiratory pressure physiotherapy for airway clearance in people with cystic…

A new study published in the journal e-LIFE has taken a novel approach to looking at deficits in protein folding associated with mutations in the CF transmembrane conductance regulator (CFTR) gene, the underlying cause of cystic fibrosis (CF). By identifying the signaling networks controlling protein folding, the study opens…

Cystic Fibrosis News Today has covered news of the latest treatments, events, clinical trials, and research updates in cystic fibrosis on a daily basis throughout the past year. As 2015 comes to an end, here are 10 articles most widely read by Cystic Fibrosis News Today readers, each with a brief summary of the developments that…

A new study of children with cystic fibrosis found that co-infection with methicillin-resistant bacteria may be associated with increased pulmonary morbidity, especially in children with repeat hospitalizations. The retrospective study, conducted at a U.S. pediatric medical center with high rates of methicillin-resistant respiratory infections, is titled “Clinical characteristics and…

In a new study, researchers investigated the CFTR gene locus (its location and position in DNA) and the role of elements involved in regulating the chromatin structure and gene expression, discovering a mechanism that coordinates these regulatory elements and maintains normal gene expression levels when structural perturbations occur. The findings…

A Case Western Reserve University researcher is starting two studies, based on angiotensin signaling and gene “correction,” to advance research into more effective ways of treating cystic fibrosis (CF) and to better understand the ideal timing for such interventions. Both studies will begin in January. CF is due to a defective gene that causes a thick buildup…