A philanthropic donation to Emory University will contribute to the research of new therapies for cystic fibrosis (CF) at the laboratory of Dr. Eric J. Sorscher, a scientific leader in cystic fibrosis research. Sorscher heads a research program at Emory and Children’s Healthcare in Atlanta that focuses on discovering…
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The Mayo University Hospital in Ireland has a new €1.4 million day care center for young cystic fibrosis (CF) patients, a much-needed addition in a country with the highest incidence and highest carrier rate of CF in the world. The center, which opened on Jan. 15, 2016, was developed through collaboration between…
The drug ivacaftor appears to be safe for children 2 to 5 years old with specific types of a cystic fibrosis (CF) genetic mutation, according to recent U.K. research. The findings support the drug’s U.S. approval for youngsters in this age group, and also indicate a potential period in early life when organ…
A study reported that treating a mouse model of cystic fibrosis (CF) with the antibiotic streptomycin eased the animals’ airway hyper-responsiveness. The improvement in airway function was accompanied by an altered immune profile and changes in a certain bacteria in the gut. The study, titled “Streptomycin treatment…
Ian Ross Pettigrew, the Hamilton, Ontario-based photographer and the creator of the Salty Girls photo project and book of the same name, is carrying on with the next stage of his project: capturing images of people living with cystic fibrosis (CF). Salty Kids will containing a gallery of images of children with…
Nivalis Therapeutics announced that the U.S. Food and Drug Administration (FDA) has granted its lead investigational drug, N91115, orphan drug status for the treatment of cystic fibrosis (CF). Drug candidate N91115 is a stabilizer of the CF transmembrane conductance regulator (CFTR) protein. Orphan drugs are generally those with a limited…
A recent study in the American Journal of Critical Care Medicine suggested a new therapeutic target for cystic fibrosis (CF), and reinforced the idea that inflammation is an acquired response unrelated to the CFTR genetic mutation. The study is titled “X-Box–Binding Protein 1 and Innate…
Vertex Pharmaceuticals, a biotech company that discovers, develops, and commercializes medicines for a series of diseases, currently with a clinical development program focused on cystic fibrosis (CF), recently announced its key business priorities for 2016. Vertex currently has two medicines approved for cystic fibrosis treatment: KALYDECO (ivafactor) and ORKAMBI (lumacaftor/ivacaftor).
University of New Mexico researcher Graham Timmins has developed a diagnostic breath test, known as the urease test, that has the potential to rapidly confirm diseases like tuberculosis (TB) by detecting bacterial enzymes (ureases) in the lungs. The test was developed for TB, but Dr. Timmins plans to investigate its efficacy in other lung…
A recent study published in the journal Pediatrics showed that depression in parents of children with cystic fibrosis (CF) negatively impacts treatment adherence in children taking enzyme supplements. The findings point to the possibility of increasing adherence rates by identifying and treating parental depression. Studies showed that good…
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