Author Archives: Kara Elam

Researchers from the University of Queensland (UQ), Australia, have recently released findings from their scientific literature review in an effort to identify all cases of Burkholderia pseudomallei infections in cystic fibrosis (CF) patients globally, the potential risk factors for acquisition, clinical consequences, and optimal treatment strategies. The findings entitled, “An international,…

This week, Vertex Pharmaceuticals Incorporated, a global biotechnology company that aims to discover, develop and commercialize innovative new medicines for diseases such as cystic fibrosis, announced that the U.S. Food and Drug Administration (FDA) has accepted for review a supplemental New Drug Application (sNDA) for the use of…

AmpliPhi BioSciences Corporation, a global leader in the development of bacteriophage-based antibacterial therapies to treat drug resistant infections, announced study results for a trial looking at a novel treatment strategy for cystic fibrosis (CF) patients. The results, which suggested that bacteriophages remain active against Pseudomonas aeruginosa (P. aeruginosa)…

An article published in the Journal of Clinical Microbiology provides important clues to understanding the cause of pulmonary exacerbations in patients with Cystic Fibrosis (CF).  The study, entitled, “Analysis of changes in diversity and abundance of the microbial community in a cystic fibrosis patient over…

An article published in BioMed Central’s Pulmonary Medicine journal provides evidence that the impaired immune system, a key feature in cystic fibrosis (CF), may lead to patients being deprived of necessary oxygen due to lung tissue destruction. The study, entitled “Hypoxia down-regulates expression…

An article published in the Journal of Clinical Investigation provides evidence that challenges the previously held assumptions as to where the abnormal accumulation of sticky mucus, a key feature in cystic fibrosis (CF), originates. The study entitled “Defective goblet cell exocytosis contributes to murine cystic…

An article published this week in the new edition of Annals of the American Thoracic Society, provides an essential overview of health indicators that are important to patients diagnosed with cystic fibrosis (CF). Study investigators from University of British Columbia, School of Population and Public…