OrPro Therapeutics, Inc. has announced it has been granted a patent by the US Patent and Trademark Office (USPTO) for its lead candidate Theradux™, covering its unique treatment ability for cystic fibrosis (CF). The company has been developing a treatment pipeline based on thioredoxin, a naturally secreted protein with enzymatic activity known to have…
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Vertex Pharmaceuticals, Inc. and CRISPR Therapeutics have announced that they will collaborate on drug research and development using CRISPR’s proprietary gene editing technology CRISPR-Cas9 to discover novel, potential treatments that address the underlying genetic causes of diseases such as cystic fibrosis (CF). The collaboration between Vertex and CRISPR will evaluate the use…
The burden of cystic fibrosis (CF) is both physical and psychological for those with the disease — a struggle that many people are unaware of. Photographer Ian Pettigrew recently published the book Salty Girls to capture CF patients’ everyday reality and to celebrate the women who suffer…
Persons with Cystic Fibrosis (CF) between ages 11 and 25 who think they can help inspire and engage other young people living with CF are being invited to check out a new program from the U.K.’s Cystic Fibrosis Trust. The Trust is reaching out to young people living with CF…
New research has revealed potential, new strategies to fight against P. aeruginosa infection and improve both survival and quality of life in patients with cystic fibrosis. The study, entitled “Normal and Cystic Fibrosis Human Bronchial Epithelial Cells Infected with Pseudomonas aeruginosa Exhibit Distinct Gene Activation Patterns” was published in the …
Contrary to previous research, in a recent study published in the journal BMC Pulmonary Medicine, scientists did not find any general elevated risk for anxiety and depression among patients with Cystic Fibrosis. In people with CF, a defective gene causes a thick buildup of mucus…
A new study revealed that adaptive changes in Pseudomonas aeruginosa may exacerbate pulmonary inflammation and contribute to the pathogenesis and progression of chronic lung disease in the context of cystic fibrosis. The study entitled “Cystic fibrosis–adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses” was published in July in the Science Advances journal.
A new study entitled “A novel siderophore system is essential for the growth of Pseudomonas aeruginosa in airway mucus” published in the Scientific Reports journal by researchers from the PLUS Project for Medical Science and Yonsei University College of Medicine in Seoul, Korea, identified a genetic element that codifies…
The British non-profit organization Cystic Fibrosis Trust has launched a survey entitled “Cystic Fibrosis & Treatment – What Matters to You?” for patients to share their thoughts and needs regarding treatment for cystic fibrosis (CF). With the motto “Use your voice to support access to transformational treatments,”…
Galapagos NV, a clinical-stage biotechnology company specialized in the discovery and development of small molecule medicines with novel modes of action for treating diseases such as cystic fibrosis as well as inflammation and other indications, recently announced that its drug candidate GLPG2665 has been chosen to be developed as a next-generation…
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