Researchers at the University of Missouri–Columbia have discovered two key amino acids in the protein that is associated with cystic fibrosis (CF) — cystic fibrosis transmembrane conductance regulator (CFTR) protein. The study is entitled “Localizing a gate in CFTR” and was published in the journal…
News
New Research Into Bacterial Behavior Could Aid in Mitigating Antibiotic Resistance in CF Patients
Researchers from The University of Texas at Austin recently revealed that the pathogenic bacteria Pseudomonas aeruginosa has the capacity to inhibit its own growth and the growth of antibiotic-resistant mutants. The study entitled “The spatial profiles and metabolic capabilities of microbial…
Caleigh Haber is an artist, blogger and the focus of this month’s Happiness Stories video series. To celebrate Cystic Fibrosis Awareness Month, the series is sharing the story of Caleigh, who despite living with cystic fibrosis (CF), tries to always see…
Two Phase III clinical trials from Northwestern University’s Feinberg School of Medicine and Stanley Manne Children’s Research Institute at Ann Robert H. Lurie Children’s Hospital of Chicago tested a combination treatment plan in patients with cystic fibrosis. The results show that lumacaftor/ivacaftor, to be marketed under the…
14 year-old Chilean teenager Valentina Maureira became internationally known when she posted a video on YouTube asking the government’s permission to end her life. Valentina suffered from cystic fibrosis, and a month after her plea to the Chilean President Michelle Bachelet was refused, she died from complications associated…
The cystic fibrosis (CF) community will get a firsthand look at the anticipated findings of the Wave 1 multi-dose trial conducted by the Gene Therapy Consortium (GTC), which includes the University of Oxford’s Gene Medicine Group, the University of Edinburgh’s Centre for Molecular Medicine and Roslin Institute, and Imperial College…
An international research team led by researchers at the Sapienza University of Rome in Italy reported that the assessment of daily physical activity in adult patients with cystic fibrosis (CF) could be used as a valuable tool to determine their aerobic fitness and exercise performance. The study was published in…
During the American Thoracic Society 2015 International Conference being held in Denver, Colorado, 15-20 of May, researchers from Oregon State University, Corvallis (OSU), and Aradigm Corporation will present a study entitled “Treatment of Mycobacterium Avium Subsp Hominissuis (MAH) Lung Infections with Liposome-Encapsulated Ciprofloxacin Resulted in Significant Decrease in Bacterial Load in the…
After the Pulmonary-Allergy Drugs Advisory Committee (PADAC) met to discuss the approval of Orkambi, members of the committee voted 12 to 1 recommending Vertex Pharmaceuticals’ new treatment for cystic fibrosis to be approved by the US Food and Drug Administration for marketing. The indication is for cystic…
Results from a recent study conducted by a team of researchers from the University of Pennsylvania’s Perelman School of Medicine indicate that only half of women with a diagnosis of cystic fibrosis (CF) use contraceptives and often opt for unplanned pregnancies. The study findings were presented last week during the…
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