News

Gene Editing Corrects CF Mutation in Multiple Organs All at Once

A novel gene-editing treatment platform corrected the mutation that causes cystic fibrosis (CF) in multiple tissues throughout the bodies of mice, according to results of a first-of-its-kind study. “This is the first study looking at treating multiple organs affected by CF with a single gene editing treatment administered intravenously,” Alexandra…

Trikafta Treatment Clears Aspergillus Fungus in CF: Pilot Study

Trikafta, a triple therapy combining elexacaftor, tezacaftor, and ivacaftor, cleared Aspergillus fungus in the lungs and prevented severe infections in children and adults with cystic fibrosis (CF), a pilot study found. “These preliminary results are very encouraging and support the hypothesis that initiation of [Trikafta] therapy rapidly improves…

Anti-inflammatory Medications in CF May Help Reduce Lung Bacteria

A new study suggests that the use of anti-inflammatory medications to modulate immune signaling proteins in people with cystic fibrosis (CF) may potentially reduce bacteria and avoid antibiotic resistance. Researchers found that different bacteria in the airways of CF patients induced the release of varying signaling proteins, called cytokines,…

Vitamin C Boosts Activity of Vitamin E in CF

Vitamin C supplements can increase how long vitamin E stays active in the body in people with cystic fibrosis (CF), a small study suggests. “It would seem to be clinically prudent for CF clinicians and nutritionists to recognize the importance of dietary and supplemental vitamin C levels and their…