News

Getting vaccinated against Coxsackie B viruses (CVB) may help prevent people with cystic fibrosis (CF) from getting ill, according to a new study of CF mouse models. “This study shows that CVB infections are common in the CF population and we provide preclinical evidence that CVB infections are preventable…

Young patients with cystic fibrosis (CF) who have a lung infection caused by Staphylococcus bacteria may have worse lung function and more exacerbations than those who are infected with Pseudomonas bacteria, a Brazilian study has found. The study, “Lower airway microbiota and decreasing lung function in young Brazilian…

Voting is now open for the 2022 Thriving Undergraduate and Thriving Graduate Scholarships — a grant program for students with cystic fibrosis (CF) that is run by AbbVie. This year marks the 30th anniversary of the scholarships program, which annually awards a total of $25,000 each to one…

Treatment with ELX-02 in combination with Kalydeco (ivacaftor) was well-tolerated, but failed to meet efficacy goals in a clinical trial that tested the combo in people with cystic fibrosis (CF) caused by nonsense mutations. Eloxx Pharmaceuticals, the company developing ELX-02, says the lack of efficacy may…

Acne might be a side effect of Trikafta therapy in cystic fibrosis (CF) patients, according to a new case series in the U.S. Trikafta (elexacaftor, tezacaftor, ivacaftor) is a CFTR (cystic fibrosis transmembrane conductance regulator) modulator that helps the defective CFTR protein function more effectively in CF…

Use of Kaftrio (elexacaftor, tezacaftor, and ivacaftor), sold in the U.S. as Trikafta, helped a woman with cystic fibrosis (CF) more easily become pregnant and maintain her health throughout the pregnancy and child’s birth, according to a case report from France. The woman had struggled in a previous pregnancy, due to…

Supplemental oxygen lessened the abundance of some microbial species in sputum samples from people with cystic fibrosis (CF) while sparing others, including Pseudomonas aeruginosa and Staphylococcus aureus, the main causes of bacterial lung infections in patients, a study reported. A need for caution exists when using supplemental oxygen, “historically ……

People with cystic fibrosis (CF) who have abnormal glucose tolerance — higher-than-normal blood sugar levels after eating — are more likely to experience clinical exacerbations of worsening lung function, according to a new study. This was found to be true even for patients who don’t meet the criteria for…

First Wave BioPharma has developed a new optimized formulation of adrulipase, a yeast-derived enzyme designed to treat exocrine pancreatic insufficiency in people with cystic fibrosis (CF). The new formulation ensures that the enzyme is packed in acid-resistant micro-granules and protected from the acid environment of the stomach. The enzyme then reaches…

In children with cystic fibrosis (CF), certain genetic variants were found to be associated with the rate of absorption of the antibacterial agent ciprofloxacin — used to prevent bacterial infections, mainly those caused by Pseudomonas aeruginosa — according to a new study. Researchers believe that these new data will…