Cystic fibrosis climate checklist: What to consider when traveling

Last updated July 22, 2025, by Roslyn Marano
Fact-checked by Inês Martins, PhD

People with cystic fibrosis (CF) can and do travel the world, but safe and enjoyable travel takes a bit of extra planning. Beyond what goes in your suitcase, it’s important to think about how different climates might affect your health.

Things like air quality, altitude, humidity, temperature, and allergens can all influence how you feel and how well you breathe. These factors can also raise the risk of lung infections or dehydration if you’re not prepared.

No matter your age or CFTR mutation type (a genetic change that causes CF), planning ahead for climate-related risks can help you stay healthy while you’re away from home.

Air quality and pollution

Poor air quality from things like smoke or dust can worsen breathing and raise the risk of lung infections, including Pseudomonas aeruginosa (a type of bacteria that can cause serious illness in people with CF).

Before traveling, check the Air Quality Index (AQI), a score that indicates the level of air pollution, using tools like AirNow.gov and IQAir. An AQ over 100 is considered unhealthy for sensitive groups.

Some regions also face environmental risks specific to CF — such as vog (volcanic smog) in Hawaii or airborne fungal spores in desert climates — which may not be reflected in a basic AQI report.

It’s helpful to ask your care team about any known risks associated with your destination. If forecasts look poor, pack a N95 mask that filters out fine particles, bring your medications, and plan some indoor activities.

Altitude and oxygen levels

At high altitudes, the air has less oxygen. This can make it harder to breathe, especially for people with lung conditions.

A high-altitude simulation test, which checks how your body responds to lower oxygen levels, may be recommended before air travel or mountain trips.

Your CF team can advise whether supplemental oxygen is necessary during your flight or stay.

Temperature and hydration

In hot, humid places, people with CF lose more salt through sweat, which increases the risk of dehydration.

Drink water regularly, even if you don’t feel thirsty. Ask your provider if electrolyte drinks or salt tablets are recommended for your activity level and climate.

Cold and dry climates can also cause the nose and lungs to dry out. This can irritate the lungs and make you more susceptible to respiratory infections. A scarf can help warm the air before you breathe it, and a humidifier (a device that adds moisture to the air) or nasal sprays can keep your airways more comfortable.

Allergens, mold, and water safety

Pollen and mold can trigger allergy or asthma symptoms. People with CF who also have allergies may notice worse sinus or breathing issues during certain seasons.

Water safety is another important consideration. People with CF may need to avoid hot tubs and still bodies of water, such as lakes or ponds, due to the high risk of bacterial infection, especially if they have a port, PICC line, or other medical device. Even keeping the device dry does not eliminate the risk.

Some areas also have high levels of nontuberculous mycobacteria (NTM) in water and soil, which can cause lung infections. Consider checking local advisories or asking your pulmonologist about specific travel concerns.

General travel tips

Talk to your CF care team before your trip, especially if you are traveling to high elevations or a great distance. Ask them if they recommend any specific vaccines or safety protocols.

As for what to pack, aside from general travel essentials, be sure to remember:

a summary of your medical info and medications
a portable nebulizer (a device that turns liquid medicine into mist) and backup batteries
extra enzymes, salt tablets, and any necessary prescriptions
contact info for local CF clinics or hospitals.

Climate travel checklist for CF patients

When planning your next vacation, work your way through this checklist to ensure your travels aren’t disrupted by environmental triggers or unexpected health challenges.

Check the AQI before traveling, and limit outdoor activity if the air quality is poor.
Talk to your healthcare provider about high-altitude simulation testing before flying or visiting elevated areas.
Stay well-hydrated in hot weather and take steps to replenish salt lost through sweat.
In cold or dry climates, use a scarf to warm the air you breathe, and consider using a humidifier or nasal spray.
Monitor pollen and mold levels, especially during allergy seasons, and bring any necessary allergy medications.
Avoid hot tubs, lakes, and other still water sources, as they can harbor bacteria that increase the risk of infection.
Research environmental risks specific to your destination, such as fungal spores or NTM exposure.
Identify nearby medical facilities or CF care centers in case you need help while traveling.

With good planning, people with CF can enjoy traveling safely and confidently. A few simple steps can make a big difference.

Cystic Fibrosis News Today is strictly a news and information website about the disease. It does not provide medical advice, diagnosis, or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.