How Chronic Illness Affected My Education

In a previous column, I explained that I was diagnosed with mycobacterium abscessus — one of the deadliest infections for cystic fibrosis (CF) patients — in my junior year of college, and how that was one of the many times that my chronic illness affected my education. I was…

P. Aeruginosa Bacterium May Adapt to Become More Resistant

Pseudomonas aeruginosa, the most common bacterium infecting the lungs of people with cystic fibrosis (CF), appears to go through a number of changes that enables it to adapt during the course of an infection, a study says. Using samples of sputum (mucus brought up from the airways by…

P. Aeruginosa Metabolites May Enable Better Patient Management

Molecules produced by the environmental bacteria Pseudomonas aeruginosa, called alkyl-quinolones derivatives — which regulate bacterial gene activity and act in cell-to-cell communication — may be useful markers for better management of patients with cystic fibrosis (CF), a study suggests. These derivatives also may enable a more clear definition…

Clinical Trial Planned for Cystic Fibrosis Bacteria Treatment AIR001

The University of Pittsburgh has agreed to conduct a Phase 1 and 2 clinical trial of Aries Pharmaceuticals‘ AIR001 for treating Pseudomonas aeruginosa bacteria infections in patients with cystic fibrosis (CF). Researchers from the university and the University of Pittsburgh Medical Center will work together on the open-label safety and proof-of-concept trial. Aries, a…