Phase 2 Trial Testing SPI-1005 for Ototoxicity in CF Patients Moving Forward

Sound Pharmaceuticals (SPI) has enrolled its first-patient-in — meaning the first subject meeting the criteria for inclusion and exclusion of a clinical study — in a Phase 2 trial testing SPI-1005 for the prevention and treatment of tobramycin-induced ototoxicity in cystic fibrosis (CF) patients, the company announced. Tobramycin…

#NACFC — Sound Pharmaceuticals to Present Preliminary Data on Ototoxicity Study

Sound Pharmaceuticals (SPI) will present data on the incidence and severity of ototoxicity in cystic fibrosis (CF) patients who received tobramycin for the treatment of acute pulmonary exacerbations. The presentation, which was accepted as a late-breaking abstract, will be given at the upcoming North American Cystic Fibrosis…

Enrollment Underway in CF Clinical Trial for Ear Toxicity Caused by Antibiotics

The first study of cystic fibrosis (CF) patients who received antibiotics that caused inner ear disease or ototoxicity is enrolling participants, according to Sound Pharmaceuticals. The Phase 1b STOP Ototoxicity study (NCT02819856) is led by Dr. Patrick Flume, MD,…