Posts by: Ashraf Malhas, PhD

cystic fibrosis, News

Analysis of blood glucose levels in cystic fibrosis (CF) patients being treated with Orkambi (ivacaftor/lumacaftor) shows that the therapy has minimal impact on glycemic control, a small study reports. Up ... Read more

July 13, 2018July 13, 2018

Awareness Needed About Importance of Early Diagnosis, Treatment of NTM Infections

cystic fibrosis, News

An earlier diagnosis and treatment of nontuberculous mycobacteria (NTM) infection in patients with cystic fibrosis (CF) may positively affect the patient’s lung function, a study suggests. NTM are a group ... Read more

April 27, 2018April 27, 2018

GERD Medicines Linked to Increased Hospitalization Risk for CF Patients

cystic fibrosis, News

Certain medications used to treat acid reflux are associated with an increased risk of hospitalization in cystic fibrosis (CF) patients, a study shows. Gastroesophageal reflux disease (GERD, aka acid reflux), ... Read more

April 25, 2018April 30, 2018

Galapagos to Start Trial Testing New Triple-Combo Therapy for CF

cystic fibrosis

Galapagos is starting a clinical trial called FALCON to evaluate a new triple-combination therapy to treat cystic fibrosis patients. The combination treatment, using experimental therapies GLPG2451, GLPG2222, and GLPG2737, all developed ... Read more

March 26, 2018June 3, 2019

Many CF Patients Have Long-term Staphylococcus Aureus Infections, Study Shows

cystic fibrosis, News

Many cystic fibrosis patients have long-term Staphylococcus aureus infections, with the bacteria’s resistance to antibiotics fluctuating over time, a study reports. Chronic and recurrent infection of the airways is the most severe ... Read more

January 16, 2018January 16, 2018

Low Chest Radiograph Scores in Young CF Children Is Associated with More Pulmonary Exacerbations, Study Says

cystic fibrosis, News

A study in young children with cystic fibrosis (CF) shows that low chest radiograph scores are associated with more frequent pulmonary exacerbations, and the use of antibiotics is beneficial when respiratory ... Read more

December 7, 2017December 7, 2017

UF Study Links Proton Pump Inhibitor Use with More Frequent Hospitalization in CF Patients

cystic fibrosis, News

Doctors should frequently re-evaluate the use of protein pump inhibitors (PPIs) for cystic fibrosis (CF) patients, urges a University of Florida study which warns that long-term PPI use leads to ... Read more

November 7, 2017November 7, 2017

#NACFC2017 – Latest Trial Data on Vertex CF Therapies and New Combos Show Benefits

cystic fibrosis, News

Vertex Pharmaceuticals recently presented data from several clinical trials of cystic fibrosis treatments showing positive outcomes for CF patients. Data focused on the approved therapies Orkambi and Kalydeco, and investigative treatments like tezacaftor/ivacaftor ... Read more

November 7, 2017November 7, 2017

#NACFC2017 – RELiZORB Effectively Normalizes Absorption of Omega-3 Fatty Acids in CF Patients

cystic fibrosis, News

A long-term clinical study showed that RELiZORB improves fatty acid absorption in patients suffering from fat malabsorption or pancreatic deficiencies, which is good news for cystic fibrosis (CF) patients suffering from ... Read more

September 19, 2017September 19, 2017

Low-dose Nitric Oxide Enhances Antibiotic Treatment of Certain Chronic CF Infections

cystic fibrosis, News

Nitric oxide (NO) inhalation can enhance the antibiotic treatment of Pseudomonas aeruginosa biofilm infections in cystic fibrosis (CF) patients, a small proof-of-concept clinical trial demonstrated. Bacterial infections by P. aeruginosa is a major ... Read more