Babies with cystic fibrosis (CF) are more likely to be born preterm — less than 37 weeks of pregnancy — and have significantly lower birth weight, according to a large study from Denmark and Wales. The study “Impact of cystic fibrosis on birthweight: a population based study of children…
News
Arcturus Therapeutics’ RNA-based approach enables the production of healthy CFTR — the protein whose dysfunction is key in cystic fibrosis (CF) — and can be effectively delivered into lung cells, according to the company’s preclinical results. This CF treatment candidate is being developed in collaboration with Cystic Fibrosis…
Grace Rose, a 15-year-old designer who was born with cystic fibrosis (CF), will host the 15th Annual Grace Rose for Cystic Fibrosis Fashion Show Fundraiser on Aug. 18 in Los Angeles to raise funds and awareness about the disease, according to a press release. Taking place at the…
Preventing a protein called AGTR2 from going about its work — either by removing it through genetic engineering or by using pharmacological agents to silence it — improved lung function in mouse models of cystic fibrosis (CF), a study reports. Earlier work linking this protein to pulmonary disease in CF patients,…
Inhaled nitric oxide (NO) was shown to be an effective antibacterial agent against Mycobacterium abscessus infection in preclinical studies, as well as in a pilot clinical trial, according to AIT Therapeutics. The company discussed the latest data on its NO product in two poster presentations during the 3rd Annual…
Five scientists whose work has been instrumental in developing disease-modifying treatments for cystic fibrosis (CF) are recipients of the 2018 Warren Alpert Foundation Prize. Until recently, therapies for CF targeted only the symptoms of the disease. The U.S. Food and Drug Administration (FDA) approved the first disease-modifying therapy, Kalydeco (ivacaftor, marketed…
A new therapy which is administered directly into the lung of viruses can kill bacteria, and was shown to be effective in reducing Pseudomonas aeruginosa infection and associated inflammation in a mouse model of cystic fibrosis (CF). This new strategy may pave the way for future treatments of…
Cystic fibrosis (CF) patients have a higher amount of harmful gut bacteria and increased levels of intestinal inflammation than healthy people, according to researchers. Their study, “Altered intestinal microbiota composition, antibiotic therapy and intestinal inflammation in children and adolescents with cystic fibrosis,” was published in the…
A natural component found in cinnamon oil, known as cinnamaldehyde or CAD, may be able to prevent Pseudomonas aeruginosa bacteria from spreading in an organism and inhibit their ability to form antibiotic-resistant biofilms, researchers show. These findings may support further study into anti-microbial medications that can help control the behavior of…
An earlier diagnosis and treatment of nontuberculous mycobacteria (NTM) infection in patients with cystic fibrosis (CF) may positively affect the patient’s lung function, a study suggests. NTM are a group of bacterial species, found in soil and water, which are not usually associated with human disease, except if they infect…
Your CF Community
Visit the Cystic Fibrosis News Today forums to connect with others in the CF community.