AllianceRx Walgreens Prime announced that it has access to a series of limited-distribution drugs (LDDs) for its specialty patients, including the recently approved Symdeko (tezacaftor/ivacaftor and ivacaftor) for cystic fibrosis (CF). Other medications available include Austedo (deutetrabenazine) for Huntington’s disease, Fasenra (benralizumab) for severe asthma, and Hemlibra…
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Vertex Pharmaceuticals is launching Phase 3 clinical trials to evaluate the safety and effectiveness of its investigational therapy, VX-445, in combination with VX-661 (tezacaftor) and Kalydeco (ivacaftor) for cystic fibrosis (CF). The AURORA program will consist of two randomized, double-blind Phase 3 trials — AURORA F/MF…
The Northeast Texas chapter of the Cystic Fibrosis Foundation (CFF) is holding its 2018 Dallas Wine Opener on Friday night, May 4, to raise money for cystic fibrosis research and improve the lives of patients and caregivers. The annual “cocktail attire” event is a gathering of more than…
Cystic Fibrosis Canada, Calgary and Southern Alberta Chapter is holding the 29th Annual 65 Roses Ladies Golf Classic event on June 25 to raise funds and awareness for cystic fibrosis (CF). The annual event will be presented by Lexus of Calgary and held at the…
Certain medications used to treat acid reflux are associated with an increased risk of hospitalization in cystic fibrosis (CF) patients, a study shows. Gastroesophageal reflux disease (GERD, aka acid reflux), which occurs when acid from the stomach rises into the esophagus causing heartburn, is more common in CF patients —…
It is now possible to identify genetic catalysts that accelerate the evolution of antibiotic resistance in bacteria, thanks to a team of researchers at University of Oxford, U.K. The findings could be used to design treatments to stop the development of antibiotic resistance. The data were published in the journal…
The new Cystic Fibrosis Innovation Hub at the University of Cambridge in the U.K. will encompass exciting new research about treatments and approaches for battling the disease, and take a “moon shot” at finding a cure. The hub is located at the University of Cambridge in the U.K. The Cystic Fibrosis…
A new population of lung stem cells capable of repairing the airways following a severe injury was identified in two preclinical studies. These cells’ ability to transform and replace several lung cell types may be explored for regenerative medicines to treat diseases such as cystic fibrosis.
The Therapeutics Development Network (TDN) of the Cystic Fibrosis Foundation has endorsed Proteostasis Therapeutics‘ trial assessing PTI-428 in combination with Symdeko (tezacaftor/ivacaftor) as a treatment for cystic fibrosis (CF). The Phase 2 trial will assess the safety, tolerability and pharmacokinetics of multiple doses of PTI-428 over a 28-day…
Enterprise Therapeutics recently closed a £29 million ($41 million) Series B financing round to help advance into clinical development the company’s pipeline of potential mucus-targeting therapies for cystic fibrosis (CF) and other lung diseases with a high unmet medical need. “We are very encouraged by progress the Enterprise team…
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