News

Australian Research Group Aiming for Better Ways of Treating Biofilm Infections

Scientists at the University of Queensland, Australia, are focusing their efforts on what is one of world’s leading sources of antibiotic resistance — biofilm. Biofilms refer to the communities of bacteria and other microorganisms that adhere to surfaces in thin layers and secrete a protective coating that diminishes the effects of antibiotics. Biofilms are considered…

Startup Raises £4 Million to Develop Mucus Clearance Treatments for CF

Enterprise Therapeutics recently announced that it has closed a £4 million (about $5 million) financing deal to accelerate the development of three new treatments  — all muco-regulatory therapies — for cystic fibrosis (CF), particularly, but also for chronic obstructive pulmonary disease (COPD) and severe asthma. “Respiratory disease remains an area of high unmet medical…

Therapy Targeting CF Mutation Appears to Restore CFTR Gene in Homozygous Patients in Study

ProQR Therapeutics is reporting that an early clinical study of  QR-010 in cystic fibrosis patients homozygous for the ΔF508 mutation in the CFTR gene met its primary endpoint. After four weeks of treatment, these patients showed a positive change in total chloride response, meaning that the CFTR protein was again working. In patients heterozygous for…

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