CF Drug Developer Vertex Announces Positive Results from Phase 2 Trial of VX-661
Adding to the excitement of Vertex Pharmaceuticals Inc.‘s new orphan drug status of VX-661 is the announcement of the results of Vertex’s Phase 2 clinical study of…
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Trial For Cystic Fibrosis Drug AZLI To Treat Chronic Burkholderia Species Infection Completed
There is some good news for cystic fibrosis patients who suffer with Chronic Burkholderia Species Infection. A Phase 3b clinical trial for Aztreonam, a therapeutic for use in CF patients with Burkholderia infections, was recently sponsored by Gilead Sciences, Inc. Gilead Sciences is a research based biopharmaceutical company engaged in…
Cystic Fibrosis, Chronic Pancreatitis Patients Claim FDA Review Of Pancreatic Enzyme Products Causing Financial Hardship
In April 2004, the Food and Drug Administration (FDA) issued a new rule requiring makers of pancreatic enzyme products (PEPs) to get their drugs approved by April 28, 2010. Unapproved pancreatic enzyme products had been available for many years, but after that cut-off date, makers of pancreatic enzyme products were required…
Xenetic Biosciences CF Drug PulmoXen Found To Be Safe, Effective In Cystic Fibrosis Patients
Xenetic Biosciences recently announced that the drug developer’s Phase I clinical trial of its new cystic fibrosis treatment PulmoXen has yielded positive results in the treatment of the disease. The announcement comes as promising news for the 30,000 patients with CF who live in the United States, and who remain…
Vertex Pivots Drug Development Focus To Cystic Fibrosis After Promising Results
A major drug developer is switching gears from Hepatitis C to Cystic Fibrosis, as Vertex’s new Proof-of-Concept Study Finds VX-661 And Kalydeco (ivacaftor) CF Drug Combination Improves Lung Function in Some Patients. For those in the cystic fibrosis patient population who follow research news for hints of the next major pharmaceutical development,…
Promising Cystic Fibrosis Therapy ARIKACE From Insmed To Treat Pseudomonas Aeruginosa Reported as Well-Tolerated In Two-Year, Open-Label Extension Study
While Cystic Fibrosis news is never in short supply, often times, many clinical trials currently underway to test experimental CF therapies are underreported by the media, who instead seek to cover fundraising and human interest stories about the disease. While these types of news articles are indeed important to…
Vertex’s VX-661 Cystic Fibrosis Drug Candidate Gets FDA Orphan Drug Status Ahead of New Clinical Trials
Vertex Pharmaceuticals continues to break new ground on developing treatments for the orphan disease cystic fibrosis. Most recently, Vertex received the FDA’s Orphan Drug Designation for its investigational drug VX-661. Orphan drug designation was established in January 1983 as a result of the Orphan Drug Act in order to encourage…
FiltersFast.com Donates $23,000 to Cystic Fibrosis Foundation
Last Saturday, April 26th, a team of hikers called Team FiltersFast.com, along with team leader and company President Ray Scardigno, took part in the Cystic Fibrosis Xtreme Hike for a Cure where they had to trek more than 30 miles in a single day along the popular Appalachian Trail. Over the last…
UVA Lab Designs Bacteria Models to Better Understand Infections in Cystic Fibrosis
Two types of bacteria have been associated with cystic fibrosis (CF):Â Burkholderia cenocepacia and Burkholderia multivorans. The two species have been found to be quite similar, in that they are both contagious, multi-drug resistant, and have an affinity for affecting immunocompromised individuals, or those diagnosed with CF. A group of…
Antimicrobial Peptide Can Exacerbate Lung Infection in Cystic Fibrosis Patients
An antimicrobial peptide produced by human immune cells may actually promote bacterial survival in cystic fibrosis patients with a chronic lung infection of Pseudomonas aeruginosa and lead to respiratory failure. The discovery was made by Daniel Wozniak and colleagues from Ohio State University Wexner Medical Center, who published a…
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