News

Trikafta, a triple therapy combining elexacaftor, tezacaftor, and ivacaftor, cleared Aspergillus fungus in the lungs and prevented severe infections in children and adults with cystic fibrosis (CF), a pilot study found. “These preliminary results are very encouraging and support the hypothesis that initiation of [Trikafta] therapy rapidly improves…

A new study suggests that the use of anti-inflammatory medications to modulate immune signaling proteins in people with cystic fibrosis (CF) may potentially reduce bacteria and avoid antibiotic resistance. Researchers found that different bacteria in the airways of CF patients induced the release of varying signaling proteins, called cytokines,…

For the second consecutive year, Owl Cyber Defense, a provider of network cybersecurity solutions, will be a presenting sponsor in the 22nd annual Swing for Cystic Fibrosis (CF) Charity Golf Classic — a tournament held to help raise awareness and funds for CF. The event is set…

Vitamin C supplements can increase how long vitamin E stays active in the body in people with cystic fibrosis (CF), a small study suggests. “It would seem to be clinically prudent for CF clinicians and nutritionists to recognize the importance of dietary and supplemental vitamin C levels and their…

The average lifespan for someone with cystic fibrosis (CF) is markedly longer in France than in Canada or Australia, a new study reports. Programs that help facilitate access to lung transplants in France may in part explain the difference, according to researchers. “For multiple reasons, which will need to…

Trikafta (elexacaftor/tezacaftor/ivacaftor) may bring health-related quality of life benefits to people with cystic fibrosis (CF) that go beyond those already reported for breathing, a study found. This expectation stems from a new look by an international team of researchers into data from the two Phase 3 clinical trials that…

The bacteria that causes chronic rhinosinusitis — swelling of the nasal cavity and sinuses — in people with cystic fibrosis (CF) are also those that often seed infections in their lungs, which means preventing or treating sinus disease may help better manage the symptoms of CF, a study suggests.

Higher weight in children with cystic fibrosis (CF) at 1 year of age, and increasing weight gain from ages 1 through 5, were correlated significantly with better lung function at age 6, according to an analysis of two large  registries. Current guidelines may need to be updated to encourage…

A measure of lung function called the lung clearance index can detect impaired lung function in children with cystic fibrosis (CF) at earlier ages than standard spirometry, a new study suggests. The study, “Pulmonary exacerbations, airway pathogens, and long-term course of lung clearance index in children…

Getting vaccinated against Coxsackie B viruses (CVB) may help prevent people with cystic fibrosis (CF) from getting ill, according to a new study of CF mouse models. “This study shows that CVB infections are common in the CF population and we provide preclinical evidence that CVB infections are preventable…