Tezacaftor may inhibit making of ceramide, key in brain development

Tezacaftor, a medication used to treat cystic fibrosis (CF), may unexpectedly trap certain fats in the lungs, diverting their use as chemical raw material that the body converts into ceramides, which are needed for the brain to develop and respond to stress, according to…

NIH Funds Fight Against CF-associated Antibiotic Resistant Bacteria

Researchers at Case Western Reserve University School of Medicine have received a $3.34 million grant from the National Institutes of Health (NIH) to develop a new strategy to sensitize Burkholderia multivorans — a common pathogen in patients with lung diseases like cystic fibrosis (CF) — to the action of…