cystic fibrosis

A new clinical study showed that AffloVest®, portable High Frequency Chest Wall Oscillation (HFCWO) vest, improved lung function scores in a cohort of adolescents with Cystic fibrosis. The study, entitled “An evidence-based study of adolescents with cystic fibrosis demonstrated that AffloVest® by International Biophysics contributed to improved…

An article published in the Journal of Clinical Microbiology provides important clues to understanding the cause of pulmonary exacerbations in patients with Cystic Fibrosis (CF).  The study, entitled, “Analysis of changes in diversity and abundance of the microbial community in a cystic fibrosis patient over…

The Medicines Company recently announced in a news release that the U.S. Food and Drug Administration (FDA) has approved the company’s supplemental new drug application (sNDA) for a new injectable formulation of the antibiotic MINOCIN® (minocycline). The news is significant for the cystic fibrosis community, as MINOCIN is…

A 39 year-old man with Cystic Fibrosis is attempting to become the first person with the disease to climb Mount Everest. Nick Talbot hopes that his perilous attempt to scale the highest and most famous mountain in the world will help to raise awareness and funds for CF while encouraging those…

DiscoveryBioMed, Inc. (DMB) has discovered and is currently developing a new class of small molecule monotherapy that utilizes the pathophysiological features of cystic fibrosis and works on two drug targets. In Cystic Fibrosis, patients’ production of the CFTR protein and ENaC ion channel is abnormal, leading to a dysfunctional CFTR activity and over-activity of ENaC.

The FDA approval of the CFTR modulator, Kayldeco, in 2012 changed the paradigm of CF healthcare by providing a therapy to address the underlying cause of the disease. The previous paradigm in CF care was limited to only treat the symptoms of CF, such as inflammation, bacterial infection and…

The residential apartment brand MCLife, which belongs to MC Companies, is launching the #CFShoeSelfie campaign, with the main purpose of raising awareness about the chronic disease cystic fibrosis (CF). At a time when emails, social media, television, and advertisements bombard everyone with images that are easily forgotten, the company aims…

Pharmaceutical company PARI Pharma received marketing authorization from the European Commission for its nebulizer Vantobra, a breakthrough therapy for patients who suffer from cystic fibrosis (CF). The product is a novel and highly concentrated tobramycin therapeutic option for inhalation that uses a Tolero nebulizer, and will now be commercialized in…

Travel Lake Anna might look like a typical travel agency dedicated to promoting vacations around Lake Anna, a state park located in Virginia. However, the company has a unique business model and purpose. Husband and wife team Chris and Laura Denkers created and manage the company in support of their two sons who were…

AffloVest, a wearable, self-contained oscillation vest device from International Biophysics that helps patients with Cystic Fibrosis breathe easier, was previously backed by numerous patient testimonies and is now proven in a new Clinical Study that it increased forced expiratory volume in one second (FEV1) an average…