CF-related diabetes (CFRD) patients are able to adhere to their treatment routines, and the condition doesn’t hurt their mental health or cognitive functioning despite posing a greater treatment burden than cystic fibrosis (CF) alone, a U.S. study found. In an analysis of almost 400 participants, people with CFRD…
News
Children with cystic fibrosis (CF) who were using CFTR modulators had lower anxiety scores than those not using the treatments, while their parents had lower anxiety and depression scores, according to a small, single-center study in Turkey. The findings suggest these treatments may be linked to mental health benefits…
For adults with cystic fibrosis (CF), long-term treatment with Trikafta (elexacaftor/tezacaftor/ivacaftor) may significantly improve the composition of bacteria living in the lungs, a study found. The study showed that with longer periods of Trikafta treatment, the community of lung bacteria (respiratory microbiota) became more diverse. Disease-causing (pathogenic) bacteria…
Kaftrio (elexacaftor/tezacaftor/ivacaftor) use was not associated with additional improvements in physical activity among children and adolescents with cystic fibrosis (CF) in a small observational study. Even so, those who started Kaftrio during the study or were already receiving it showed improvements in some health-related quality-of-life domains, including treatment…
Alyftrek, a next-generation triple-combination CFTR modulator, further improved the function of the defective CFTR protein in children ages 2 to 5 with cystic fibrosis (CF) who switched from Trikafta, new clinical trial data suggest. Vertex Pharmaceuticals, the company that markets both Alyftrek and Trikafta, presented the…
Tactile Systems Technology has announced the commercial launch of a next-generation version of its AffloVest system, a high-frequency chest wall oscillation (HFCWO) device designed to help clear mucus from the airways in people with cystic fibrosis (CF) and other chronic respiratory or neuromuscular conditions. “Commercial introduction of the…
The real-world health benefits that cystic fibrosis (CF) patients experienced when they started taking Trikafta (elexacaftor/tezacaftor/ivacaftor) during the COVID-19 pandemic were caused by the medication itself rather than lockdown safety precautions, according to a new U.S. study. Because the U.S. Food and Drug Administration approved Trikafta in…
MRI images when a patient exhales may help detect and quantify areas presumed to reflect gas trapping — an early sign of lung disease — in people with cystic fibrosis (CF), including some patients with normal results on standard lung function tests, a study found. The imaging method also…
Macrophages from people with cystic fibrosis (CF) showed multiple defects that may make it harder for them to kill infectious bacteria, a new study reports. The findings also suggest that treatment with Trikafta (elexacaftor/tezacaftor/ivacaftor) partially improved CFTR function and corrected some macrophage functions, but was not enough to…
For people with cystic fibrosis (CF), the decision of whether or not to become a parent is fraught with psychological challenges, ranging from difficult fertility treatments to deep concerns about long-term health and family stigma, a new review paper highlights. The findings underscore the critical importance of providing comprehensive…
Your CF Community
Visit the Cystic Fibrosis News Today forums to connect with others in the CF community.