News

July 15, 2020July 15, 2020

Dosing Starts in Trial of Oral Treatment, CB-280, for Chronic Lung Infections

cystic fibrosis, News

Patient dosing has begun in a Phase 1b trial evaluating Calithera Bioscience’s oral therapy CB-280 for cystic fibrosis (CF) patients with chronic airway infections, the company announced. The study (NCT04279769), currently enrolling eligible ... Read more

July 14, 2020July 14, 2020

Number of Adults With CF Likely to Grow by 28% Over Decade, UK Study Says

cystic fibrosis, News

The number of adults with cystic fibrosis (CF) living in the U.K. is expected to increase by at least 28% in 10 years, and 36% of these adults will ... Read more

July 13, 2020July 13, 2020

NIH Grant Supports Computer Modeling of Bacteria’s Behavior in Mucus

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A five-year, $3.2 million grant from the National Institutes of Health (NIH) will fund a research project that aims to better understand the interactions between bacteria and mucus. Results ... Read more

July 10, 2020July 10, 2020

Renovion’s ARINA-1 Shows Promise in Clearing Mucus, Cell Study Finds

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ARINA-1, a nebulized therapy being developed by Renovion for cystic fibrosis (CF) and other chronic inflammatory lung diseases, may be better than currently available options for clearing mucus in CF patients ... Read more

July 9, 2020July 10, 2020

Rage Biotech Opens With Goal of Treating CF and Similar Lung Diseases

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Rage Biotech, a new company building on research done at leading Australian universities, aims to develop treatments to help people with chronic inflammatory lung diseases, including cystic fibrosis, severe asthma, ... Read more

July 8, 2020July 8, 2020

Orkambi Benefits CF Patients Across Levels of Lung Health, Study Finds

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Orkambi (ivacaftor/lumacaftor) can significantly reduce the number of days people with cystic fibrosis (CF) require intravenous antibiotics for flares and helps with weight gain — independently of a patient’s level of ... Read more

July 7, 2020July 7, 2020

Common P. aeruginosa Mutations May Lead to Biofilm Growth, Bacterial Persistence, Study Says

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The common mutations that cause Pseudomonas aeruginosa to lose their ability to move are associated with a higher production of two complex sugar molecules implicated in the formation of ... Read more

July 2, 2020July 2, 2020

NuvoAir Home Monitoring System Bolsters Telemed Use in CF, Survey Finds

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Cystic fibrosis (CF) patients who monitored their lung function at home using NuvoAir‘s handheld spirometer and smartphone app were able to better engage in telemedicine, a U.K. survey found, with these ... Read more

July 1, 2020July 1, 2020

NHS, Vertex Strike Deal to Make Kaftrio Available in England

cystic fibrosis, News

NHS England and Vertex Pharmaceuticals have reached an agreement that will allow access to Vertex’s Kaftrio (ivacaftor/tezacaftor/elexacaftor), a triple combination therapy for cystic fibrosis (CF) to be used in ... Read more

June 30, 2020June 30, 2020

COVID-19 Source of Anxiety for Women With CF Children, Survey Finds

cystic fibrosis, News

Anxiety related to fears of COVID-19 infection was higher among mothers of children with cystic fibrosis (CF) than those of healthy children, although teenage patients themselves were less anxious than age-matched ... Read more