News

January 12, 2021January 12, 2021

Phase 1/2 Trial to Test Phage Therapy for Chronic P. aeruginosa Infections

cystic fibrosis, News

A Phase 1/2 clinical trial, called CYPHY, to evaluate the phage therapy YPT-01 in treating chronic Pseudomonas aeruginosa infections in people with cystic fibrosis (CF) has been initiated at Yale ... Read more

January 11, 2021January 11, 2021

CF Foundation Hosts COVID-19 Vaccine Panel Talk, Q&A on Thursday

cystic fibrosis, News

The Cystic Fibrosis Foundation (CFF) encourages cystic fibrosis (CF) patients to speak to their healthcare team about COVID-19 vaccines, in agreement with recommendations from the U.S. Centers for Disease Control and ... Read more

January 8, 2021January 8, 2021

Study Examines Effects of Socioeconomics on Health of Youngsters

cystic fibrosis, News

Children with cystic fibrosis (CF) who live in more socioeconomically disadvantaged areas of the U.S. tend to have worse lung function and health outcomes than their counterparts in more affluent ... Read more

January 7, 2021January 7, 2021

Inhaled-IV Antibiotic Combo May Better Treat Acute Flares Than IV-only Mix

cystic fibrosis, News

When given alongside the antibiotic Colistin (colistimethate), Cayston (aztreonam lysine), an inhaled antibiotic specifically targeting Pseudomonas aeruginosa, was superior to standard intravenous antibiotics at improving lung function and life quality among ... Read more

January 6, 2021January 6, 2021

Fecal Protein Tied to Worse GI Symptoms, Quality of Life in CF Children

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Elevated levels of fecal calprotectin protein, a biomarker for intestinal inflammation, was linked to worse gastrointestinal symptoms and quality of life in children with cystic fibrosis (CF), a study reports. ... Read more

January 5, 2021January 5, 2021

Health Canada Giving Priority Review to Trikafta

cystic fibrosis, News

Health Canada is reviewing an application that seeks the approval of Trikafta, a triple combination reported to treat 90% of all with cystic fibrosis (CF), or those with least one F508del mutation. ... Read more

January 4, 2021January 4, 2021

Arcturus to Develop ARCT-032 as RNA Therapy for CF

cystic fibrosis, News

Arcturus Therapeutics has selected ARCT-032, an aerosolized RNA-based therapy, to be developed as a novel therapeutic candidate for cystic fibrosis (CF). The therapy will use the company’s LUNAR delivery technology ... Read more

December 31, 2020December 31, 2020

Small Study Shows Tobramycin Safely Treats Lung Infection in Infants With CF

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Inhaled antibiotic tobramycin safely eradicated early Pseudomonas aeruginosa infection in cystic fibrosis (CF) patients younger than a year old, according to findings from a small retrospective study. The study, “Evaluation of ... Read more

December 22, 2020January 5, 2021

FDA Expands Labels for 3 Vertex CFTR Modulators

cystic fibrosis, News

The U.S. Food and Drug Administration (FDA) has expanded the number of cystic fibrosis (CF)-related mutations considered responsive to and therefore eligible for Vertex Pharmaceuticals‘ three approved therapies. With these approvals, ... Read more

December 22, 2020December 22, 2020

Antibiotic Gentamicin Can Be Effective Without Causing Deafness, Study Finds

cystic fibrosis, News

Scientists discovered the subtypes of gentamicin — a broad-spectrum antibiotic often used to treat bacterial infections in people with cystic fibrosis (CF) — that are more likely to cause deafness, ... Read more