News

Urinary Incontinence Can Rise as Women Age, Study Finds

Urinary incontinence, known to affect both girls and women with cystic fibrosis (CF), is increasingly prevalent as these patients age, and coughing or sneezing were common triggers among adults who took part in a study at a single site in Italy. Incontinence during physical exercise was also fairly common…

Self-compassion Tied to Better Quality of Life in Adults With CF

People with cystic fibrosis (CF) who score highly on measures of self-compassion tend also to report higher quality of life, a study found. “The current findings suggest that psychological interventions which increase self-compassion could be beneficial for enhancing better mental health and quality of life for adults with CF,”…

Lung and Nutritional Health, Like CF Mutation, Can Affect Lifespan

Inadequate nutrition, poorly working or chronically infected lungs, and mutations leading to more severe disease can shorten the lifespan of people with cystic fibrosis (CF), a study in adult patients reported. “All these factors interact with each other,” its scientists wrote. “Therefore, it is important to take into account…

Way of Creating Bile Duct Cells May Help to Treat CF Liver Disease

Researchers generated functional bile duct cells from human-derived stem cells that can be used to support the development of therapies for liver disease in people with cystic fibrosis (CF), a study reported. “These studies highlight the importance of generating mature cells from stem cells that faithfully mimic the functional…

Trikafta Increases Microbiome Diversity in Lungs, Study Shows

The microbiome diversity in the lungs of cystic fibrosis (CF) patients increased after treatment with Trikafta, becoming similar to a person without CF, an analysis showed. In addition, small molecule metabolites produced by cells varied widely across patients while on the therapy, with the largest decrease seen in…

Lung Airway Chip Accurately Models Cystic Fibrosis

For the first time, many features of cystic fibrosis (CF) were modeled accurately in a human Lung Airway Chip lined with cells from CF patients, which included enhanced mucus secretion, inflammation, and microbial infections, a study has shown. This “organ-on-a-chip model” of the disease may support the rapid development…


Featured Column

How to Ask for and Offer Help

A banner for Kate Delany's "Breathe and Believe" column that depicts a pair of lungs with flowers blossoming from them.
In times of need, we may not know how to ask for help or offer it to others. Columnist Kate Delany shares helpful tips on how to do it.

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