News

New target may aid antibiotics in treating M. abscessus infection

A newly identified therapeutic target showed a potential to enhance the effectiveness of antibiotics against resistant Mycobacterium abscessus (Mabs) lung infection, a damaging complication in people with cystic fibrosis (CF), researchers report. Experiments using human airway organoids derived from CF patients also accurately reflected many features seen in their…

Adults using Kalydeco, Trikafta show lung function, nutrition gains

Adults using Kalydeco (ivacaftor) or Trikafta (ivacaftor/tezacaftor/elexacaftor) to treat their cystic fibrosis (CF) showed gains in lung function and nutritional status, according to a real-world, observational study in Australia. In contrast, no significant improvements in lung function were seen in adults or children with CF using Orkambi (ivacaftor/lumacaftor)…

Children as young as 2 now may use digestion aid Relizorb

The U.S. Food and Drug Administration (FDA) will allow children with cystic fibrosis (CF) as young as age 2 to use Relizorb, an enzyme cartridge that connects with an enteral feeding tube to provide easier digestion of fats. “This additional RELiZORB clearance represents access for approximately 25% of…

Support groups, clear advice needed by parents living with CF

As more adults with cystic fibrosis (CF) choose to become parents, they face unique challenges in balancing the responsibilities of caring for their children and managing their disease, a study highlights. Researchers outlined several areas where care teams could be of help, such as working with prospective parents to…

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