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April 4, 2019April 4, 2019

Resura, First Prenatal Non-Invasive Test for Single-Gene Diseases Like CF, Launched by Progenity

cystic fibrosis, News

Resura Prenatal Test, the first non-invasive prenatal test for single-gene (monogenic) disorders such as cystic fibrosis (CF), has been launched by biotech company Progenity. The test screens fetal cell-free ... Read more

April 3, 2019April 3, 2019

Phase 2a Trial Will Test Molgradex in CF Patients with NTM Infections

cystic fibrosis, News

Savara Pharmaceuticals has launched a Phase 2a clinical study to evaluate the effectiveness of Molgradex in cystic fibrosis (CF) patients with chronic nontuberculous mycobacterial (NTM) lung infections. Molgradex is an ... Read more

April 2, 2019April 2, 2019

Virus that Infects Bacteria Turns Immune Response Away from P. aeruginosa, Study Shows

cystic fibrosis, News

Pseudomonas aeruginosa, the most common bacteria found in cystic fibrosis (CF) patients, uses a virus to go unnoticed by the host immune system, a new study shows. Treatment with ... Read more

April 1, 2019April 1, 2019

Canadian CF Patients Have Better Lung Function, But More Abnormal Glucose Metabolism Than French Patients, Study Reports

cystic fibrosis, News

Canadian patients with cystic fibrosis (CF) have better respiratory function and higher body mass index (BMI) than French patients, although they have higher blood glucose levels and a greater ... Read more

March 29, 2019March 29, 2019

Eloxx Presents More Positive Preclinical Data for ELX-02, Potential CF Treatment

cystic fibrosis, News

Eloxx Pharmaceuticals presented new positive preclinical data for ELX-02, its lead treatment candidate for cystic fibrosis (CF), demonstrating that the therapy increases the levels of CFTR protein and its ... Read more

March 28, 2019March 28, 2019

Costs for CF Therapies Could Double in 2019, According to Pharmacy Benefit Manager

cystic fibrosis, News

Costs for approved cystic fibrosis (CF) treatments and new approvals — including therapies extended to more age groups or targeting new mutations — could double in price, according to ... Read more

March 27, 2019March 27, 2019

Triple Combo of Proteostasis’ CFTR Modulators May Benefit CF Patients, Phase 1 Trial Shows

cystic fibrosis, News

Treatment with Proteostasis Therapeutics’ triple combo therapy regimen may significantly improve the lung function of patients with cystic fibrosis (CF), results from a Phase 1 clinical trial suggest. The ... Read more

March 26, 2019March 26, 2019

Asthma Medicine Xolair Successfully Treats Lung Allergy Due to Fungal Infection in 3 CF Patients, Case Report Shows

cystic fibrosis, News

Xolair (omalizumab), a medicine used for allergic asthma and chronic hives, is effective for treating lung allergic reactions caused by fungi in patients with cystic fibrosis (CF), a case ... Read more

March 25, 2019March 25, 2019

Targeting Bacteria Cell Wall Elements Can Fight Chronic P. aeruginosa Infection, Study Suggests

cystic fibrosis, News

Targeting some elements in the bacterial cell wall can be an effective way to activate the immune system and fight chronic, treatment-resistant Pseudomonas aeruginosa infections, according to a study. ... Read more

March 22, 2019March 22, 2019

New Strategy May Boost Antibiotics’ Efficacy in CF Patients, Study Suggests

cystic fibrosis, News

Removing a key metabolite called pyruvate from Pseudomonas aeruginosa and Staphylococcus aureus bacteria biofilms — two of the most common bacteria found in cystic fibrosis (CF) patients — could ... Read more

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