News

August 28, 2020August 28, 2020

Trikafta’s Arrival in Canada Could Cut CF Deaths by 15% Over 10 Years, Study Suggests

cystic fibrosis, News

If Trikafta — Vertex Pharmaceuticals’ next-generation triple combination cystic fibrosis (CF) therapy — were to be available in Canada next year, the median age of CF patients could rise by 9.2 ... Read more

August 27, 2020August 27, 2020

Proteostasis Therapeutics Merges With Yumanity Therapeutics

cystic fibrosis, News

Proteostasis Therapeutics (PTI) has entered into a definitive merger agreement with Yumanity Therapeutics to leverage their common expertise about protein misfolding to advance the development of disease-modifying therapies for several ... Read more

August 26, 2020August 26, 2020

CF Foundation Awards Nearly $15 Million to Groups Researching Infections and CF

cystic fibrosis, News

The Cystic Fibrosis Foundation (CFF) has awarded nearly $15 million to 33 organizations that are researching how to improve outcomes for cystic fibrosis (CF) patients who are battling infections. ... Read more

August 25, 2020August 25, 2020

Muscles of CF Youth Consume Oxygen Faster Than Peers, Affecting Exercise

cystic fibrosis, News

Poorer oxygen uptake and transport may underlie skeletal muscle differences that affect exercise tolerance in children and adolescents with cystic fibrosis (CF) relative to healthy peers, a recent study ... Read more

August 24, 2020August 24, 2020

Vertex Triple Combo, Kaftrio, Approved for CF Patients in EU With F508del Mutation

cystic fibrosis, News

The European Commission (EC) approved Kaftrio (ivacaftor/tezacaftor/elexacaftor) in combination with Kalydeco (ivacaftor) to treat cystic fibrosis (CF) in people 12 and older who have either two F508del mutations or one F508del mutation ... Read more

August 21, 2020August 25, 2020

NuvoAir Home Platform Classified as Class Im Medical Device

cystic fibrosis, News

Note: This story was updated Aug. 25, 2020, to clarify that, according to NuvoAir, the regulatory entity in question is the European Medical Device Directive. The NuvoAir Home platform, ... Read more

August 20, 2020August 21, 2020

FDA Grants Orphan Drug Designation to KB407, Potential Gene Therapy for CF

cystic fibrosis, News

The U.S. Food and Drug Administration (FDA) has granted the designation of orphan drug to KB407, Krystal Biotech’s potential inhaled gene therapy for the treatment of cystic fibrosis (CF). ... Read more

August 18, 2020August 19, 2020

Work Proudly Program to Help 15 CF Patients or Caregivers Find Flexible Jobs

cystic fibrosis, News

The nonprofit Claire’s Place Foundation has launched a pilot program to help 15 adults with cystic fibrosis (CF) or caregivers of patients acquire flexible employment, enabling them to continue working while dealing ... Read more

August 17, 2020August 17, 2020

First Patients Enrolled in Phase 2b Trial Testing MS1819 for Exocrine Pancreatic Insufficiency in CF

cystic fibrosis, News

AzurRx BioPharma has enrolled the first three patients in its Phase 2b trial investigating MS1819 as a treatment for exocrine pancreatic insufficiency (EPI) in cystic fibrosis (CF) patients. The ... Read more

August 14, 2020August 14, 2020

MS1819-PERT Combo Shows Benefits for CF Patients With EPI in Phase 2 Trial

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MS1819, AzurRx BioPharma’s investigational treatment for exocrine pancreatic insufficiency (EPI) associated with cystic fibrosis (CF), safely increased fat absorption in the first five patients receiving the therapy alongside pancreatic ... Read more