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June 10, 2020June 16, 2020

PROMISE Study Examines Trikafta Use Among CF Patients

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In the seven months since Vertex Pharmaceuticals’ triple-combo therapy Trikafta (elexacaftor/tezacaftor/ivacaftor) hit the market, people with cystic fibrosis, their doctors, and the Cystic Fibrosis Foundation (CFF) have all given ... Read more

June 9, 2020June 15, 2020

Suppressing Function of Chloride Channel TMEM16A Eyed as Potential Therapeutic Approach

cystic fibrosis, News

Researchers have reported the case of two siblings with impaired CFTR function due to a deficiency in another chloride channel, called TMEM16A, that do not present symptoms associated with ... Read more

June 8, 2020June 8, 2020

Viral Makeup of Intestines in CF Children Altered, May Drive Inflammation

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Children with cystic fibrosis (CF) have an altered intestinal virome, or viral communities, compared to healthy children that may impact growth and intestinal inflammation, a case-control study reported. The ... Read more

June 5, 2020June 5, 2020

Encala Improves Fat Absorption in CF Patients With Pancreatic Insufficiency, Study Shows

cystic fibrosis, News

Investigational treatment Encala (Lym-X-Sorb) is safe, well tolerated, and increased dietary fat absorption in patients with cystic fibrosis (CF) and pancreatic insufficiency, according to an analysis from a Phase ... Read more

June 3, 2020June 3, 2020

Georgia College Student Receives AffloVest from Legacy Project

cystic fibrosis, News

A deputy sheriff’s squad car, lights ablaze and sirens blaring, recently raced to Benjamin Clackum’s house on a sleepy residential street in Lawrenceville, Georgia, but no one was getting ... Read more

June 2, 2020June 2, 2020

CF Registry in UK Collecting Data on COVID-19 Infections

cystic fibrosis, News

During COVID-19, the U.K. Cystic Fibrosis Registry is taking steps to further the collection of data on how the ongoing pandemic is affecting people with cystic fibrosis (CF). The CF ... Read more

June 1, 2020June 1, 2020

Pravibismane Receives FDA Orphan Drug Status for Treatment of CF Lung Infections

cystic fibrosis, News

Pravibismane suspension, a new type of inhaled antimicrobial medication developed by Microbion, has received orphan drug designation from the U.S. Food and Drug Administration (FDA) for the treatment of lung ... Read more

May 29, 2020May 29, 2020

Mobile PERT App Helps Improve Quality of Life for Children With CF, Study Shows

cystic fibrosis, News

MyCyFAPP, a mobile app designed to help patients with cystic fibrosis (CF) manage their pancreatic enzyme replacement therapy (PERT) regimen, can improve the quality of life of children with ... Read more

May 28, 2020May 28, 2020

Real-world Use of Kalydeco for CF Highly Effective, Large-scale Analysis Shows

cystic fibrosis, News

Kalydeco treatment led to fewer deaths, transplants, hospitalizations, and exacerbations in people with cystic fibrosis (CF) compared to patients who did not receive the therapy, according to a five-year, ... Read more

May 27, 2020May 27, 2020

Microbe DNA Discovery May Lead to Noninvasive Test for CF Infections

cystic fibrosis, News

People with cystic fibrosis (CF) have higher levels of DNA from common microbes that cause CF-related infections circulating in their blood compared to healthy controls, a study discovered. These ... Read more