News

January 7, 2020January 7, 2020

Don’t Overlook Importance of Sleep Hygiene, CF Experts Advise

cystic fibrosis, News

People with cystic fibrosis (CF), like their healthy counterparts, often neglect sleep. But that can lead to problems down the road, warned three CF experts at the 2019 North ... Read more

January 3, 2020January 3, 2020

Gene Variations May Explain Resistance to Lung Infections in Some CF Patients, Study Says

cystic fibrosis, News

Genetic variations that lower the expression levels of a gene called RNF5 may explain why some people with cystic fibrosis (CF) are at lesser risk of developing lung infections, a ... Read more

December 27, 2019December 27, 2019

CFF Programs Strive to Reduce Patients’ Isolation

cystic fibrosis, News

Oregon retiree Carol Birch, 59, considers herself especially lucky to have made it this far in life. “I’ve never felt that I fit the typical role of someone with ... Read more

December 25, 2019December 25, 2019

Chronic Kidney Disease Highly Prevalent in CF, Kidney Function Poorer in Transplanted Patients, Italian Study Says

News

Patients with cystic fibrosis (CF) have a high prevalence of chronic kidney disease (CKD) linked to higher levels of uric acid and fats in the blood, a study has ... Read more

December 19, 2019December 19, 2019

Proteostasis’ Triple Combo Improves Lung Function in CF Patients, Phase 2 Trial Shows

cystic fibrosis, News

A triple combination of dirocaftor (PTI-808), Proteostasis Therapeutics’ investigational CFTR potentiator, with a proprietary CFTR amplifier and corrector led to significant improvements in lung function in patients with cystic ... Read more

December 16, 2019December 16, 2019

Diet to Help Manage Glucose in CF Patients: A Nutritionist’s View

News

It is well documented that patients with cystic fibrosis (CF) are a vulnerable population as far as nutrition is concerned. Daily energy needs for CF patients are typically one ... Read more

December 13, 2019January 15, 2020

Proteostasis to Test Personalized Treatment with Novel CFTR Modulators in Europe

cystic fibrosis, News

Three investigative therapies by Proteostasis Therapeutics — PTI-801, PTI-808, and PTI-428 — showed potential to treat cystic fibrosis (CF) patients ineligible for approved CFTR modulators after patient-specific lab models ... Read more

December 12, 2019January 15, 2020

CFF Offers Emotional Send-off to Retiring CEO Preston Campbell

cystic fibrosis, News

Preston W. Campbell III, MD, recently bid farewell as president and CEO of the Cystic Fibrosis Foundation (CFF) in Nashville — the same city where he began his long ... Read more

December 11, 2019December 11, 2019

European Commission Approves Kalydeco for Children as Young as Six Months

cystic fibrosis, News

The European Commission has approved a label extension for Kalydeco (ivacaftor), allowing the therapy to be used in infants with cystic fibrosis (CF) who are between the ages of ... Read more

December 10, 2019December 10, 2019

Kalydeco Improves Lung Function in Patient Carrying Responsive and Non-responsive Mutations, Case Study Reports

cystic fibrosis, News

Treatment with Kalydeco (ivacaftor) alone improved lung function and quality of life in a cystic fibrosis patient carrying both a therapy-responsive and a non-responsive mutation to treatment, a case study ... Read more