CF Patients Being Recruited for Phase 1 Study of Oral CFTR Amplifier
Proteostasis Therapeutics announced it is now enrolling cystic fibrosis patients and healthy adults in two Phase 1 clinical trials evaluating its lead drug candidate PTI-428. PTI-428 is an oral amplifier of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Amplifiers are CFTR modulators that selectively increase the amount of an…