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Treatment with the CFTR modulator Kalydeco (ivacaftor) led to significant weight gain, suggesting better nutritional status, in  babies and toddlers with cystic fibrosis (CF) eligible for this therapy’s use, a study reports. “Young children experienced favorable changes in weight gain and some nutritional biomarkers in the first 12…

A protein from scorpionfish might combat antibiotic-resistant bacterial infections in cystic fibrosis (CF) patients, a recent study suggests. The human version of the protein, called bactericidal/permeability-increasing protein (BPI), normally works to fight off bacteria, but people with CF have self-reactive antibodies that destroy it. In lab studies, the scorpionfish…

The Cystic Fibrosis (CF) Foundation will put up to $2 million into an effort by Nosis Bio to use artificial intelligence (AI) to design carriers that can safely deliver gene therapy into the lungs of people with CF. “This type of therapy has the potential to treat anyone with…

Anxiety and depression are more likely in younger cystic fibrosis (CF) patients with CF-related diabetes and more evident mental health challenges, a long-term study in teenagers and young adults reported. Poorer lung function is considered to affect mental health with CF, and the lung health of these patients…

Claire’s Place Foundation is encouraging supporters to “light up the night” as part of its 9th annual Glow Ride for Cystic Fibrosis on Aug. 12 to help defray living expenses for cystic fibrosis (CF) patients and their families. In addition to the Hermosa Beach, California, event, an…

Undernutrition, or not getting enough nutrients to meet the body’s needs, may occur in as many as half of hospitalized children with cystic fibrosis (CF), making it more common than in other chronic diseases, a study finds. The study, “Undernutrition is still highly frequent in hospitalized children…

A new adrulipase formulation for people with cystic fibrosis (CF), designed as a treatment for exocrine pancreatic insufficiency or EPI — when the small intestine is unable to fully digest food due to problems with digestive enzymes from the pancreas — was deemed safe and well tolerated in a…

More lumps of fat and hardened deposits, called calcifications, may show up on imaging scans of the pancreas of people with cystic fibrosis (CF) who have diabetes, a study shows. These findings suggest doctors can use computed tomography (CT) imaging to help diagnose CF-related diabetes and distinguish these…

Being treated with Kaftrio or Symveki led to a reduced need for insulin in people with cystic fibrosis-related diabetes (CFRD), a small study found. The treatment wasn’t associated with alterations in blood sugar and associated factors in CF patients without diabetes. The findings add to a growing…

People with cystic fibrosis (CF) who were underweight before treatment gained the most weight after six months on Trikafta (elexacaftor/tezacaftor/ivacaftor), according to a new study. Underweight participants, as assessed with the body mass index (BMI), also saw the biggest gains in treatment-related lung function. Patients who were overweight…