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Scorpionfish protein may treat antibiotic-resistant infections

A protein from scorpionfish might combat antibiotic-resistant bacterial infections in cystic fibrosis (CF) patients, a recent study suggests. The human version of the protein, called bactericidal/permeability-increasing protein (BPI), normally works to fight off bacteria, but people with CF have self-reactive antibodies that destroy it. In lab studies, the scorpionfish…

Study: Underweight CF patients see biggest weight gains with Trikafta

People with cystic fibrosis (CF) who were underweight before treatment gained the most weight after six months on Trikafta (elexacaftor/tezacaftor/ivacaftor), according to a new study. Underweight participants, as assessed with the body mass index (BMI), also saw the biggest gains in treatment-related lung function. Patients who were overweight…