News

Low Aerobic Capacity Linked to Higher Risk of Exacerbations

Cystic fibrosis (CF) patients with lower aerobic exercise capacity — assessed with a non-invasive cardiopulmonary exercise test — have a 4.5 times higher risk of future pulmonary exacerbations, according to a small 10-year study in Greece. Aerobic capacity, or VO2peak, is the maximal amount of oxygen a person’s…

Vertex CF Treatments Opening to Eligible Patients in France and Italy 

Vertex Pharmaceuticals has reached reimbursement agreements with health authorities in France and Italy for its various cystic fibrosis (CF) treatments, including Kaftrio (ivacaftor/tezacaftor/elexacaftor), a next-generation therapy approved for use with ivacaftor. With these agreements — which bring the treatments into each country’s public health program — about 3,000 CF patients…

Joint Disease More Common With P. aeruginosa Infection, Female Sex

Chronic Pseudomonas aeruginosa infection in adults with cystic fibrosis increases their likelihood of developing CF arthropathy, a painful inflammation of the joints, a German study reported. Additional risk factors for CF arthropathy include older age, female sex, and more severe disease. These findings were published in the Journal of Cystic Fibrosis, in…