Author Archives: Vanda Pinto

Boehringer Acquires Rights to Potential CF Inhalation Gene Therapy

Boehringer Ingelheim has taken legal steps giving it the lead role in further development of a long-lasting, inhalation gene therapy for cystic fibrosis (CF), called BI 3720931, that stems from a public-private research effort begun in 2018. The 2018 agreement brought together Boehringer, the U.K. Cystic Fibrosis…

Minorities With CF Have Worse Lung Function, Study Says

Blacks and Hispanics with cystic fibrosis (CF) have worse lung function than white patients, according to a study from New York City. However, no differences were found among these groups of patients in several other parameters, including the number of visits to the doctor, treatments with antibiotics, and hospitalizations. The…

Metal in Source Water Tied to NTM Infection in Patients in Colorado

Source water levels of a metal called molybdenum is a significant environmental risk factor for nontuberculous mycobacteria (NTM) infection among people in Colorado with cystic fibrosis (CF), a database study focused on that state reported. NTM infection, caused by Mycobacterium abscessus (M. abscessus), is a difficult-to-treat bacterial infection, and…

Tobramycin Given in Nanoparticles May Best Treat P. aeruginosa

A new biomaterial made up of nanoparticles showed a potential to improve — by up to 100,000 times — the efficiency of tobramycin, an antibiotic used to treat cystic fibrosis (CF) patients with Pseudomonas aeruginosa infections. Tobramycin, carried within a nanostructured material, completely eradicated P. aeruginosa infection in a…

Orkambi Shows Long-term Safety, Efficacy in Children Ages 2-5

Long-term use of Orkambi (lumacaftor/ivacaftor), an approved cystic fibrosis (CF) treatment, is safe and effective for children between ages 2 and 5 with two copies of the disease-causing F508del mutation in the CFTR gene, a study reported. It draws on results from a Phase 3 open-label extension trial…

Featured Column

Don’t Overlook Emotional Wellness When Dealing With Chronic Illness

A banner for Lara's column, depicting a car on a road trip winding through a forest.
Living with a chronic illness can affect emotional wellness, writes columnist Lara Govendo, who offers up some ideas for managing both.

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