Routine blood tests can accurately predict the development of an allergic response to the fungus Aspergillus in children with cystic fibrosis (CF), a study suggests. A higher risk of the lung allergic response, called allergic bronchopulmonary aspergillosis (ABPA), was found among those with elevated biomarker levels for up…
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Children with cystic fibrosis (CF) have lower gut levels of certain short-chain fatty acids (SCFAs), metabolites made by beneficial gut bacteria that help regulate inflammation, a study reports. The researchers also found that children with CF had lower dietary fiber intake, reduced gut microbial diversity, fewer key SCFA-producing bacteria,…
Handgrip strength was associated with breathing muscle strength in adults with cystic fibrosis (CF), according to a new study, suggesting the simple test may help complement standard lung function tests in clinical care. The research also found that lung function and breathing muscle strength were related to a combination…
Short-term increases in air pollution can trigger pulmonary exacerbations — disease flares marked by a sudden worsening in lung function — in people with cystic fibrosis (CF), a new study shows. Notably, the study found that increased pollution doesn’t trigger exacerbations right away — the data suggest that…
Treatment with Trikafta (elexacaftor/tezacaftor/ivacaftor) may do more than improve the function of a faulty protein in people with cystic fibrosis (CF). According to a new study from Italy, the triple-combination therapy may also help reduce chronic inflammation, known to contribute to long-term lung damage in those with CF.
The amount of physical activity children and adolescents with cystic fibrosis (CF) get is linked to their age, physical abilities, screen time, and several other everyday factors, according to a recent study. Other factors tied to physical activity included taking part in organized sports, having social support from others,…
Levels in the bloodstream of certain circulating microRNAs — small strands of genetic material that help regulate gene activity — may flag changes linked to cystic fibrosis-related diabetes (CFRD), or its development, in people with cystic fibrosis (CF). That’s according to a new study by researchers in Europe…
About one-quarter of children with cystic fibrosis (CF) who are hospitalized for pulmonary exacerbations — an acute worsening of lung symptoms, often marked by increased cough and thicker or more mucus — will temporarily develop pulmonary hypertension (PH), a condition marked by high pressure in blood vessels that…
Kidney failure, when the kidneys no longer work on their own, is up to 29 times more common in people with cystic fibrosis (CF) than in the general U.S. population. That’s according to a recent study, which also identified diabetes and complications associated with lung transplant as the most…
Trikafta safely improved lung function and reduced exacerbations in people with cystic fibrosis (CF) who started treatment after age 40, a study found. Some participants no longer had Pseudomonas aeruginosa or methicillin-resistant Staphylococcus aureus (MRSA), bacteria that are major contributors to CF lung disease. “Overall, our study…
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