European Cystic Fibrosis Society (ECFS) president and Cystic Fibrosis Trust professor Stuart Elborn was one of the contributors of the latest breakthrough in cystic fibrosis (CF) research, and he believes that the positive results of two phase 3 studies of the drugs ivacaftor (Kalydeco) and lumacaftor may…
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The majority of patients suffering from cystic fibrosis (between 80-90% of the patient population) are affected by exocrine pancreatic insufficiency (EPI), a condition usually present at birth and commonly diagnosed within their first year of life. However, a new experimental therapy for the condition has shown to be…
A fundraising event at the Hyatt Regency Huntington Beach on Saturday, July 19th attracted more than 800 people and became a record-setting fundraising event for the Cystic Fibrosis (CF) Foundation, collecting $1.2 million in donations to help find a cure for the chronic disease. The seventh annual “Pipeline to…
San Francisco based KaloBios Pharmaceuticals, Inc. on Monday released an update on the status of its KB001-A monoclonal antibody development program, including news that multinational Sanofi Pasteur, which had been collaborating with Kalobios on the KB001-A R&D program, is pulling out of the partnership. KaloBios will regain all…
Experimental Drug For the Treatment of CF May Lead to Potential Treatment of CF-related Diabetes
With more than half of the patients with cystic fibrosis developing diabetes and most of them exhibiting insulin insufficiency, researchers at the Chinese University of Hong Kong conducted a study to explain this relationship and suggest a potential treatment strategy for CF-related Diabetes. The study, published this month in…
Findings of new study led by Martina Gentzsch, PhD, at the University of North Carolina School of Medicine and the UNC Marsico Lung Institute in Chapel Hill, N.C. could help drug developers improve compounds designed to correct CFTR proteins in cystic fibrosis (CF) patients. In lab experiments…
Doctors and pharmacists are constantly on the lookout for potential drug interactions when giving patients medication. As a result of a number of recent in vitro cell studies, a few cystic fibrosis treatments may soon be added to the list of interactions. Two independent teams found some cystic fibrosis transmembrane…
According to a recent study conducted by a medical student from Manchester University in the United Kingdom, approximately 50 percent of cystic fibrosis patients are also infected by the Aspergillus fungus, which is caused by an exposure to mold. The research highlights the dangers of mold, and it may help doctors improve diagnosis…
Researching and developing therapies to help patients survive cystic fibrosis (CF) remains one of the main goals of a number of CF research centers and biotech organizations worldwide. However, for the Cystic Fibrosis Lifestyle Foundation, an organization founded in 2003, their goal is to address the…
To find another valuable tool to evaluate the efficacy of the commonly prescribed cystic fibrosis drug ivacaftor (Kalydeco from Vertex Pharmaceuticals), a team from The Ohio State University College of Medicine and Nationwide Children’s Hospital in Columbus, Ohio, tested high resolution computed tomography (HRCT) with cystic fibrosis…
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