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Almost 30% of cystic fibrosis (CF) patients who had a lung transplant in the U.S. were prescribed Trikafta after surgery, a recent analysis shows. Sinus disease and low body mass index (BMI), a measure of body fat that takes into account weight and height, were associated with receiving…

Grants that provide financial assistance for nutrition may help people with cystic fibrosis (CF) maintain a healthy body weight, according to a study whose findings emphasize clinicians’ role in making sure patients know about the resources available to them. “The results of our study highlight the importance of active…

Men with cystic fibrosis (CF) are generally knowledgeable about how their disease affects fertility, but they still want to be able to talk about their reproductive options with their providers, who may be uncomfortable or unskilled with these discussions, particularly with teens.. The findings indicate a need for more…

Health Canada has approved the next-generation CFTR modulator therapy Alyftrek for people 6 years and older with cystic fibrosis (CF) who have at least one mutation that’s responsive to the therapy. That includes the most common CF-causing mutation, F508del. The approval in Canada follows similar approvals in…

All eligible cystic fibrosis (CF) patients in England can now receive Vertex Pharmaceuticals’ CF treatment Alyftrek (vanzacaftor/tezacaftor/deutivacaftor), after the company reached a reimbursement agreement with the National Health Service (NHS). The decision follows a positive recommendation from the National Institute for Health and Care Excellence and the treatment’s…

The first participant has been dosed in a Phase 2b clinical trial testing BiomX’s experimental inhaled therapy BX004 in adults with cystic fibrosis (CF) and chronic Pseudomonas aeruginosa lung infection. “This first patient dosing marks a significant milestone for our BX004 program and for CF patients with chronic P.

Among methods used to diagnose cystic fibrosis (CF) in France, newborn screening (NBS) was associated with the lowest healthcare expenses during the first year of life, according to a large, population-based study. Fewer inpatient hospitalizations primarily drove the lower costs when infants were diagnosed via NBS, the data showed.

Women with conditions such as cystic fibrosis (CF) who planned their pregnancies after a lung transplant experienced better outcomes compared with those who did not plan their pregnancies, according to a recent study. Those positive outcomes included longer gestation periods, higher birth weights of their babies, and a lower…

Delivering gene-editing tools to mice while they were still developing in the womb corrected the mutated CFTR gene that causes cystic fibrosis (CF), with the correction lasting into adulthood and restoring normal protein function in the lungs and digestive system, a study found.  While it’s still too early…

Alyftrek has been approved by the European Commission to treat cystic fibrosis (CF) patients 6 years and older who have at least one non-class 1 mutation in the CFTR gene. This indication in the European Union (EU) represents the broadest label for Alyftrek (vanzacaftor/tezacaftor/deutivacaftor) in the world, according to the…