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An increase in body mass index (BMI) in people with cystic fibrosis (CF) under Kaftrio therapy may not be attributable to increased energy intake, according to a new U.K. study. Instead, gains in BMI, a measure of body fat, might reflect other factors, such as different energy requirements…

Hispanic cystic fibrosis (CF) patients are at a higher risk of developing Staphylococcus aureus lung infections — and at a younger age — than are non-Hispanic white patients, according to a new U.S. study. The analysis also indicated that Hispanic CF patients, on average, develop both antibiotic-responsive and…

A Chicago children’s hospital is leading an awareness campaign to reduce the missed or delayed diagnosis of cystic fibrosis (CF) after newborn screening, especially in non-white infants. “Delays in diagnosis of cystic fibrosis increase the risk for severe illness,” Susanna McColley, MD, principal investigator and a pulmonologist at the…

One year of treatment with hypertonic saline, inhaled twice daily, reduced the thickness of the airway walls in children with cystic fibrosis (CF), according to an analysis of clinical trial data. Researchers used an automated method to assess changes in lung structure captured on CT scans, and supported…

Treatment with the CFTR modulator Kalydeco (ivacaftor) led to significant weight gain, suggesting better nutritional status, in  babies and toddlers with cystic fibrosis (CF) eligible for this therapy’s use, a study reports. “Young children experienced favorable changes in weight gain and some nutritional biomarkers in the first 12…

A protein from scorpionfish might combat antibiotic-resistant bacterial infections in cystic fibrosis (CF) patients, a recent study suggests. The human version of the protein, called bactericidal/permeability-increasing protein (BPI), normally works to fight off bacteria, but people with CF have self-reactive antibodies that destroy it. In lab studies, the scorpionfish…

The Cystic Fibrosis (CF) Foundation will put up to $2 million into an effort by Nosis Bio to use artificial intelligence (AI) to design carriers that can safely deliver gene therapy into the lungs of people with CF. “This type of therapy has the potential to treat anyone with…

Anxiety and depression are more likely in younger cystic fibrosis (CF) patients with CF-related diabetes and more evident mental health challenges, a long-term study in teenagers and young adults reported. Poorer lung function is considered to affect mental health with CF, and the lung health of these patients…

Claire’s Place Foundation is encouraging supporters to “light up the night” as part of its 9th annual Glow Ride for Cystic Fibrosis on Aug. 12 to help defray living expenses for cystic fibrosis (CF) patients and their families. In addition to the Hermosa Beach, California, event, an…

Undernutrition, or not getting enough nutrients to meet the body’s needs, may occur in as many as half of hospitalized children with cystic fibrosis (CF), making it more common than in other chronic diseases, a study finds. The study, “Undernutrition is still highly frequent in hospitalized children…