Adults with cystic fibrosis, compared with healthy individuals, have poorer diet quality and increased accumulation of visceral adipose tissue, which is associated with higher sugar intake and fasting glucose levels, a study reports. The study, “Visceral adipose tissue is associated with poor diet quality and higher fasting glucose in adults…
cystic fibrosis
The American Thoracic Society (ATS) recommends the use of home oxygen therapy in children with cystic fibrosis (CF) who have mild or severely reduced oxygen saturation, according to the most recent guidelines. ATS clinical guidelines for home oxygen therapy use in pediatric patients with lung and pulmonary vascular…
Stimulation of neurons accounts for approximately half of the beneficial production of airway surface liquid (ASL) induced by hypertonic saline (HTS), a therapeutic agent used for cystic fibrosis (CF) treatment, according to research. The study, “Nebulized hypertonic saline triggers nervous system-mediated active liquid secretion in cystic fibrosis swine…
Cystic Fibrosis Canada — Calgary and Southern Alberta Chapter will hold the 30th Annual 65 Roses Ladies Golf Classic event on June 17 to raise funds and awareness for cystic fibrosis (CF). The automotive dealership Lexus of Calgary will present the event, to be held at the Earl Grey…
Patients with cystic fibrosis (CF) whose lungs have never been colonized by the Pseudomonas aeruginosa bacterium have a milder form of the disease, a retrospective study based on registry data suggests. The study, “Clinical and microbiological characteristics of cystic fibrosis adults never colonized by Pseudomonas aeruginosa: Analysis of the French…
Health Canada has approved the use of Kalydeco (ivacaftor) in toddlers age 1-2 years with certain genetic mutations that prevent the correct functioning of the CFTR protein, the therapy’s developer announced. With a pill taken twice a day, Kalydeco, by Vertex Pharmaceuticals, makes it possible to resolve the underlying…
New personalized strategies that can address the nutritional needs of cystic fibrosis patients may provide the best care and improve patient outcomes, a study suggests. The study, “A survey identifying nutritional needs in a contemporary adult cystic fibrosis cohort,” was published in the journal BMC Nutrition.
The Cystic Fibrosis Foundation (CFF) will fund the preclinical development of two gene therapy candidates, Talee Bio’s TL-101 and TL-102, for the treatment of cystic fibrosis (CF), the company announced. Talee will receive up to $4.5 million from CFF to help accelerate the development of both these gene therapies…
The Horizon 2020 research and innovation program of the European Union granted €6.8 million (approximately $7.7 million) to an international research team for the development of non-viral gene delivery technology. This new gene therapy strategy has the potential to improve the health of patients with genetic diseases worldwide, including…
The European Commission has approved the label extension of Orkambi (lumacaftor/ivacaftor) for the treatment of children ages 2-5 with cystic fibrosis (CF) due to F508del mutations, Vertex Pharmaceuticals, the therapy’s manufacturer, announced. Orkambi was previously approved in Europe to treat CF patients 6 and older with the…
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