Cystic fibrosis (CF) is a condition known to be linked to lung problems, but bone health can also be impacted in people with the disease. A new paper from researchers in the United Kingdom focuses on this problem. The report, “Bone health and disease in cystic fibrosis,“…
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A recent study from Belgium showed that a common bacterium found in the lungs of people with cystic fibrosis (CF) might be converted to a less dangerous form, and could possibly aid in the development of treatments for the disease. The research report, “Effect of Shear Stress on Pseudomonas aeruginosa Isolated…
The San Diego Chapter of the Cystic Fibrosis Foundation will host its inaugural Surf for CF day on the beach at La Jolla Shores on Sept. 24, raising awareness and funds for cystic fibrosis (CF). The two-part event will feature free surf lessons for 25 cystic fibrosis patients in the morning,…
Spine deformities that are sometimes seen in cystic fibrosis (CF) may be adequately corrected with minimal risk through multidisciplinary care during surgery and meticulous surgical techniques, as reported by a case study reviewed in the article “Scoliosis Surgery in Cystic Fibrosis: Surgical Considerations and the Multidisciplinary Approach of a Rare Case.”
Canadian patients with cystic fibrosis (CF) will have to wait for access to Orkambi (lumacaftor/ivacaftor), whose submission will be reconsidered at a future meeting by the Canadian Drug Expert Committee (CDEC) of the Canadian Agency for Drugs and Technologies in Health (CADTH). CADTH is the nonprofit Canadian organization that makes recommendations for a…
The Cystic Fibrosis Foundation Therapeutics (CFFT) recently awarded Laurent Pharmaceuticals a Therapeutics Development Award, valued to up to $3 million, to support a Phase 2 clinical trial evaluating the company’s drug candidate, LAU-7b, as a potential treatment for cystic fibrosis (CF). “People with CF have an exaggerated and persistent inflammatory response to…
All babies with a known mutation causing cystic fibrosis (CF) and a second mutation known as the 5T allele should be screened for additional mutations to predict their risk of developing CF later in life, according to a study conducted by researchers at Children’s Hospital Los Angeles (CHLA), Brigham and Women’s Hospital (BWH), and the California Department of Public Health.
The Cystic Fibrosis Foundation hosted more than 100 researchers from various fields at its “New Technologies Advancing Toward a One-time Cure” conference last month to debate how new research and treatments for genetic diseases across the board could lead to a cure for cystic fibrosis (CF), an inherited condition in which the lungs and digestive system can…
When patients with cystic fibrosis (CF) breathe in small amounts of bile, some bacterial species switch to a chronic infection mode, aiding both bacterial colonization of the airways and the development of antibiotic resistance. The study, “Bile signalling promotes chronic respiratory infections and antibiotic tolerance,” published in the…
Suppressing a specific type of immune cell called Th17 may aid cystic fibrosis (CF) patients with Pseudomonas aeruginosa infection, one of the most common infections in CF, as suggested by findings of a recent study in mice. The study, “Antiinflammatory effects of bromodomain and extraterminal domain inhibition in cystic…
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