Cases of severe COVID-19 remained low during the first year of the pandemic in people in France with cystic fibrosis (CF), a study reported. Patients with severe lung disease or CF-related diabetes, as well as those who underwent a lung transplant, however, were at a higher risk of…
Scientists at the University of Southampton have created a new method that could be useful for rapidly identifying infectious bacteria in samples from people with cystic fibrosis (CF). Unlike currently used methods, this method does not require a time-consuming culture step where bacteria are grown in a laboratory. The…
Some people with severe asthma, an inflammatory lung condition, carry variants of the CFTR gene that causes cystic fibrosis (CF), a genetic study found. These findings support the genetic assessment of severe asthma patients with CF-related symptoms, the scientists recommended. The study, “DNA Sequencing Analysis of…
Problems with the CFTR protein — which causes cystic fibrosis (CF) — limit the replication and spread of SARS-CoV-2, the virus that causes COVID-19, in cells of the lung’s airways to protect patients, a study suggests. Cells lacking the CFTR gene responsible for that protein…
A natural compound called ectoine may help to improve the stability of the CFTR protein by modulating the activity of a molecular signaling pathway called AREG-EGFR-ERK, a study reported. Ectoine is a stress-protection molecule with water-retaining and potentially anti-inflammatory properties. The researchers suggested that ectoine, given in combination with CFTR…
CF-370, an expeimental therapy by ContraFect, reduces the number of hard-to-treat Pseudomonas aeruginosa bacteria in a rabbit model of pneumonia, an infection that inflames the lungs. P. aeruginosa, the most common cause of lung infections in people with cystic fibrosis (CF), can evade the body’s immune…
Patients, family, friends, and caregivers will come together this May for Cystic Fibrosis (CF) Awareness Month to educate the public about the condition and raise money for research and care. A number of CF organizations have events planned throughout the month, including the largest U.S.-based nonprofit, the Cystic Fibrosis…
A Russian military plane crash near Tetiana Zamorska’s home in Kyiv, Ukraine, was a sign that it was time for her and her family to leave. The treacherous, 34-hour pilgrimage that ultimately brought the group of eight by car to temporary accommodations in neighboring Poland last month was physically and emotionally difficult,…
Inspired by a cousin who lives with cystic fibrosis (CF), a University of Central Florida (UCF) undergraduate student will use a $4,000 Cystic Fibrosis Foundation (CFF) grant to seek better treatments for the genetic disease that affects the lungs and other organs. The young researcher, Sahiba Ahmed,…
A lung and pancreatic cell transplant from a single donor to people with end-stage cystic fibrosis (CF) and CF-related diabetes (CFRD) safely and effectively improved their lung function, metabolic control, and quality of life, data from a small Phase 1/2 trial show. Given that CFRD increases the risk of complications…
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