News

Ivacaftor, a component of the triple-combination therapy Trikafta, is essential to restore mucus clearance in people with cystic fibrosis (CF), a study reports. The study was launched after previous work using CF airway cells suggested that long-term exposure to ivacaftor limited the restoration of CFTR, the protein…

Metered-dose inhalers that use potent greenhouse gases to propel medicines into the lungs of people with cystic fibrosis (CF) have the worst environmental impact across all types of inhalers, according to a new study from researchers in Spain. The team noted that propellants in metered-dose inhalers are hydrofluorocarbons, potent…

At least three months of Kaftrio treatment reduced liver stiffness, an indicator of liver fibrosis, in school-age children and adolescents with cystic fibrosis (CF), according to a real-world study in Sweden. The benefits were particularly prominent among children who had signs of CF-related liver disease (CFLD) before starting Kaftrio,…

Home-based spirometry — a test to measure how well the lungs are working — provides results that are almost as reliable as those taken in a hospital, and such testing could help people with cystic fibrosis (CF) monitor their condition without as many visits to the doctor, a study…

The Clairity Ball — the hallmark annual event of Claire’s Place Foundation — is set to return to Southern California later this month with an evening of fundraising that will bring together celebrities and champions of the cystic fibrosis (CF) community. The nonprofit’s May 31 ball, to…

Long-term Trikafta treatment led to improved lung function, fewer respiratory symptoms, and lower sweat chloride levels — elevated levels are a key hallmark of cystic fibrosis (CF) — in children with CF, ages 6 to 11, according to new findings from a two-year extension study. Trikafta was…

Regular exercise improves fitness in adults with cystic fibrosis (CF), and treatment with Kaftrio — a combination of elexacaftor, tezacaftor, and ivacaftor that’s marketed as Trikafta in the U.S. — may help patients engage more in higher-intensity physical activity, a German study suggests. The study, “Effects of…

The events slated for this year’s Cystic Fibrosis Awareness Month aim to celebrate the accomplishments, milestones, and hopes of those in the cystic fibrosis (CF) community. During May, U.S. and international organizations are encouraging people with CF to share their experiences and challenges, helping others picture what the future…

People with diabetes related to cystic fibrosis (CF) who had better long-term sugar control were more fit, a study found, suggesting that keeping blood sugar within normal limits may help improve the ability to exercise. The study, “The association between dysglycaemia and exercise capacity in cystic fibrosis,” was…

Treating expectant mothers with CFTR modulators may help to reduce the risk of intestinal complications for babies with cystic fibrosis (CF), according to a small real-world study from France. “We hope that such a study, merged with other international programmes, will also provide support for the European Medicines…