News

Using inhaled antibiotics can help control the growth of certain bacteria in the lungs, but it may increase the risk of fungal infections with Aspergillus fumigatus in people with cystic fibrosis (CF), according to a study. The study, “Association between inhaled antibiotic use and treatment-emergent organisms among Canadian people with cystic fibrosis,”…

The Cystic Fibrosis Foundation (CFF) has awarded $5 million to the Cleveland Clinic to continue as the biorepository coordinating center for the Cystic Fibrosis Lung Transplant Consortium until 2030, supporting research and other efforts to improve lung transplant outcomes. Created in 2017, the consortium has established a…

Scientists have discovered a potential therapy for cystic fibrosis (CF) patients who are infected with Mycobacterium abscessus, a bacterium that can cause serious lung infections. They found that a signaling molecule called PI5P can boost the antimicrobial activity of immune cells isolated from patients against the bacterium. This happens even…

In young children with cystic fibrosis (CF), infections with methicillin-resistant Staphylococcus aureus (MRSA) are linked to more antibiotic use, worse lung function, and more lung damage by early school age, according to a study led by researchers in Brazil. Because infections with MRSA appear to indicate more severe disease…

A personalized inhaled phage therapy targeting multidrug-resistant lung infections significantly reduces bacterial load and improves lung function in adults with cystic fibrosis (CF), according to a small study. The experimental therapy was personalized by selecting phages that worked best against Pseudomonas aeruginosa strains in patients’ sputum samples. It…

Ivacaftor, a component of the triple-combination therapy Trikafta, is essential to restore mucus clearance in people with cystic fibrosis (CF), a study reports. The study was launched after previous work using CF airway cells suggested that long-term exposure to ivacaftor limited the restoration of CFTR, the protein…

Metered-dose inhalers that use potent greenhouse gases to propel medicines into the lungs of people with cystic fibrosis (CF) have the worst environmental impact across all types of inhalers, according to a new study from researchers in Spain. The team noted that propellants in metered-dose inhalers are hydrofluorocarbons, potent…

At least three months of Kaftrio treatment reduced liver stiffness, an indicator of liver fibrosis, in school-age children and adolescents with cystic fibrosis (CF), according to a real-world study in Sweden. The benefits were particularly prominent among children who had signs of CF-related liver disease (CFLD) before starting Kaftrio,…

Home-based spirometry — a test to measure how well the lungs are working — provides results that are almost as reliable as those taken in a hospital, and such testing could help people with cystic fibrosis (CF) monitor their condition without as many visits to the doctor, a study…

The Clairity Ball — the hallmark annual event of Claire’s Place Foundation — is set to return to Southern California later this month with an evening of fundraising that will bring together celebrities and champions of the cystic fibrosis (CF) community. The nonprofit’s May 31 ball, to…