News

Treatment with Orkambi (lumacaftor/ivacaftor) for six months was found to improve exercise endurance in three adults with cystic fibrosis (CF), a new study showed. Moreover, by the end of the study, all three men experienced less leg discomfort and less dyspnea, or shortness of breath. For two patients,…

The incidence of colorectal cancer (CRC) in people with cystic fibrosis (CF) was five times higher than in those without CF, after adjusting for age, in a large-scale English population study. CFTR gene mutations, the underlying cause of CF, occurred more frequently than expected, suggesting an association between…

Prolonged use of certain medications used to treat acid reflux, called proton pump inhibitors (PPIs), may put people with cystic fibrosis (CF) at higher risk for Pseudomonas aeruginosa infection, according to a single-center study in Italy. Long-term treatment was also associated with more hospitalizations for pulmonary exacerbations, or episodes of…

Newborn genetic screening panels for variants in the CFTR gene — mutations of which are the underlying cause of cystic fibrosis (CF) — had lower detection rates in minority racial and ethnic groups in the U.S., a large-scale analysis found. Lower detection rates with genetic testing among these…

A recent overall decline in lung transplant rates for adults and children with cystic fibrosis (CF) in the U.S. has had less impact on nonwhite patients, according to a recent analysis. While transplant rates have decreased in the past couple years for all people with CF, the declines were…

Women with cystic fibrosis (CF) have different experiences with sexual and reproductive health than their peers without the disease, necessitating special considerations in their care, a new study shows. The study, “Sexual and reproductive health experiences and care of adult women with cystic fibrosis,” was published in the…

Adding a school specialist to cystic fibrosis (CF) care teams could help identify educational risk factors — and provide interventions — to promote school success for children with CF, according to a new study. That study, by specialists at a CF center in Ohio, found that more than half…

Carmine Therapeutics has completed series A financing to support the development of its innovative, non-viral gene therapy for cystic fibrosis (CF) and other diseases. The company is working to advance a novel type of disease-modifying gene therapy, which is accomplished using its proprietary Red Cell EV Gene Therapy…

The Cystic Fibrosis Foundation (CFF) opens its fourth CF FamilyCon this week, a virtual two-day free event that gives cystic fibrosis (CF) patients and their family members, caregivers, and friends an opportunity to connect, learn, and share stories of life with the genetic disorder. The Oct. 21–22 event…

The overall protein profile in the airway is altered toward a more pro-inflammatory state in people with cystic fibrosis (CF), and this difference is more pronounced in those with poorer lung function, a new study reports. “Some of these proteins might have value as markers of CF lung disease…