News

CF Foundation Funding Bolsters Gene Therapy Research

The Cystic Fibrosis Foundation is funding three new early-stage research awards worth more than $1.8 million to bolster the development of potential gene therapies for cystic fibrosis (CF). “This funding will support critical early steps necessary for the development of genetic therapies for cystic fibrosis,” William Skach, MD, executive…

Urinary Incontinence Can Rise as Women Age, Study Finds

Urinary incontinence, known to affect both girls and women with cystic fibrosis (CF), is increasingly prevalent as these patients age, and coughing or sneezing were common triggers among adults who took part in a study at a single site in Italy. Incontinence during physical exercise was also fairly common…

Self-compassion Tied to Better Quality of Life in Adults With CF

People with cystic fibrosis (CF) who score highly on measures of self-compassion tend also to report higher quality of life, a study found. “The current findings suggest that psychological interventions which increase self-compassion could be beneficial for enhancing better mental health and quality of life for adults with CF,”…

Way of Creating Bile Duct Cells May Help to Treat CF Liver Disease

Researchers generated functional bile duct cells from human-derived stem cells that can be used to support the development of therapies for liver disease in people with cystic fibrosis (CF), a study reported. “These studies highlight the importance of generating mature cells from stem cells that faithfully mimic the functional…

Trikafta Increases Microbiome Diversity in Lungs, Study Shows

The microbiome diversity in the lungs of cystic fibrosis (CF) patients increased after treatment with Trikafta, becoming similar to a person without CF, an analysis showed. In addition, small molecule metabolites produced by cells varied widely across patients while on the therapy, with the largest decrease seen in…